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PCBP1 anticorps (Internal Region)

Cet anticorps anti-PCBP1 Polyclonal Chèvre (ABIN569643) détecte spécifiquement PCBP1 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Chien.
N° du produit ABIN569643
772,31 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour PCBP1 anticorps (Internal Region) (ABIN569643)

Antigène

Voir toutes PCBP1 Anticorps
PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Reactivité

  • 49
  • 19
  • 17
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Souris, Rat, Chien

Hôte

  • 40
  • 9
  • 2
Chèvre

Clonalité

  • 31
  • 20
Polyclonal

Conjugué

  • 33
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PCBP1 est non-conjugé

Application

  • 44
  • 22
  • 12
  • 11
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 234-247, Internal Region

    Séquence

    C-ADLAKLNQVA RQQSH

    Specificité

    Recognizes PCBP1 (234-247).

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse, Rat, Canine (Dog).
    Species reactivity (tested):Human.

    Purification

    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

    Immunogène

    Peptide with sequence from the internal region of the protein sequence according to NP_006187.2. Genename: PCBP1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

    Autre désignation

    PCBP1

    Sujet

    The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.Synonyms: Alpha-CP1, HNRPE1, HNRPX, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, Poly(rC)-binding protein 1, SUB2.3, hnRNP E1

    ID gène

    5093

    NCBI Accession

    NP_006187

    UniProt

    Q15365
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