HAX1 anticorps (both Isoforms, Internal Region)
Aperçu rapide pour HAX1 anticorps (both Isoforms, Internal Region) (ABIN375096)
Antigène
Voir toutes HAX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- both Isoforms, Internal Region
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Specificité
- This antibody reacts to HAX1.
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Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence C-TRHEADSSPRGDPES, from the internal region of the protein sequence
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Indications d'application
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Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0,5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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Autre désignation
- HAX1
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Sujet
- HAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1
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ID gène
- 10456, 9606
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UniProt
- O00165
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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