ANKS1B anticorps (AA 107-268)
(5 références)Aperçu rapide pour ANKS1B anticorps (AA 107-268) (ABIN968021)
Antigène
Voir toutes ANKS1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 107-268
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Réactivité croisée
- Poulet, Souris, Rat (Rattus)
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Attributs du produit
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogène
- Human EB1 aa. 107-268
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Isotype
- IgG1
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anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 107-268) antibody
ANKS1B Reactivité: Humain, Souris, Rat, Poulet WB, IHC (p), IP, IF Hôte: Souris Monoclonal 5-EB1 unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 999-1248) antibodyANKS1B Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 245-268) antibodyANKS1B Reactivité: Humain, Souris IHC, IF (p) Hôte: Lapin Polyclonal unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 570-599) antibodyANKS1B Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB30244 unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 999-1248) antibodyANKS1B Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 182-231) antibodyANKS1B Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Porc, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 245-268) antibodyANKS1B Reactivité: Humain, Souris WB, IP, IHC (fp) Hôte: Lapin Polyclonal unconjugated
anti-Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (C-Term) antibodyANKS1B Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
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Commentaires
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Related Products: ABIN968536, ABIN967389
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 250 μg/mL
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Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store undiluted at -20°C.
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: "Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity." dans: Nature, Vol. 421, Issue 6924, pp. 753-6, (2003) (PubMed).
: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." dans: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, (2002) (PubMed).
: "Cytoplasmic linker proteins promote microtubule rescue in vivo." dans: The Journal of cell biology, Vol. 159, Issue 4, pp. 589-99, (2002) (PubMed).
: "Repression of IRF-4 target genes in human T cell leukemia virus-1 infection." dans: Oncogene, Vol. 21, Issue 44, pp. 6751-65, (2002) (PubMed).
: "Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression." dans: Cancer research, Vol. 55, Issue 7, pp. 1441-3, (1995) (PubMed).
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- ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))
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Autre désignation
- EB1
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Sujet
- Familial adenomatous polyposis is an autosomal inherited disease characterized by mutations in the APC (adenomatous polyposis coli) gene. Individuals with this disease are predisposed to colorectal polyps and cancer. It has been proposed that disruption of the APC gene plays a role in the disease. APC is a large coiled-coil protein that interacts, via its carboxy terminus, with catenins and with the protein, EB1. This 30 kDa protein was discovered as a result of its strong binding to the C-terminal domain of APC. Like the APC-binding proteins beta-Catenin and pp120Cas, EB1 may play an essential role in modulating APC activity and tumorigenesis. This antibody is routinely tested by western blot analysis.
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Poids moléculaire
- 30 kDa
Antigène
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