RPS6KA1 anticorps (AA 1-184)
(5 références)Aperçu rapide pour RPS6KA1 anticorps (AA 1-184) (ABIN967837)
Antigène
Voir toutes RPS6KA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-184
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Réactivité croisée
- Chien, Rat (Rattus), Souris, Poulet
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Attributs du produit
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogène
- Human p90[rsk] aa. 1-184
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Isotype
- IgG2a
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anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 62-321) antibody
RPS6KA1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 1-735) antibodyRPS6KA1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 4E11 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (C-Term) antibodyRPS6KA1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 1-184) antibodyRPS6KA1 Reactivité: Humain, Souris, Rat, Chien, Poulet WB, IHC, IF, IP Hôte: Souris Monoclonal 78-RSK unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (pThr359) antibodyRPS6KA1 Reactivité: Humain WB, DB Hôte: Lapin Polyclonal RB13385 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (pSer363), (pThr359) antibodyRPS6KA1 Reactivité: Humain WB, ELISA, IF, IP Hôte: Lapin Monoclonal 1B6 unconjugated Recombinant Antibody
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (Thr573) antibodyRPS6KA1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 539-588) antibodyRPS6KA1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (pSer363), (pThr359) antibodyRPS6KA1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) antibodyRPS6KA1 Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 10B1D7A9 unconjugated
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Commentaires
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Related Products: ABIN967389, ABIN968533
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 250 μg/mL
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Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store undiluted at -20° C.
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: "Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium." dans: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16113-22, (2001) (PubMed).
: "The role of the insulin receptor substrate-1 in the differentiation of rat hippocampal neuronal cells." dans: Oncogene, Vol. 20, Issue 35, pp. 4842-52, (2001) (PubMed).
: "Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis." dans: Blood, Vol. 96, Issue 13, pp. 4142-51, (2000) (PubMed).
: "Evidence that inactive p42 mitogen-activated protein kinase and inactive Rsk exist as a heterodimer in vivo." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 12, pp. 5480-4, (1994) (PubMed).
: "Mitogen-activated Swiss mouse 3T3 RSK kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of pp90rsk activity." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4981-5, (1991) (PubMed).
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- RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
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Autre désignation
- Rsk
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Sujet
- The p90[rsk] (Rsk) and p70[s6k] kinases were first identified based on their ability to phosphorylate the 40S ribosomal protein S6 in vitro. Both of these enzymes are differentially regulated by serine/threonine phosphorylation in response to mitogenic stimulation. ERK1 and ERK2 have been shown to regulate Rsk activity. Once activated by this phosphorylation, a significant amount of Rsk can be found in the nucleus, suggesting that it has a role in nuclear signaling events. The regulation of nuclear Rsk and ERK activities by growth factors is coordinated with the induction of several early response genes. Rsk has also been shown to be activated by ionizing radiation, presumably through an activated MAP kinase. Studies in Xenopus oocytes and mouse NIH/3T3 cells indicate that inactive Rsk and ERK2 exist in a complex of approximately 110kDa. Upon phosphorylation of Rsk and ERK2, the heterodimer dissociates and at least a portion of these activated kinases translocate to the nucleus.
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Poids moléculaire
- 90 kDa
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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