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AATF anticorps (N-Term)

L’anticorps anti-AATF Polyclonal Lapin est utilisé pour la détection de AATF dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Boeuf (Vache) et Porc. Il a été validé pour WB.
N° du produit ABIN183737
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour AATF anticorps (N-Term) (ABIN183737)

Antigène

Voir toutes AATF Anticorps
AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Reactivité

  • 56
  • 18
  • 13
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Boeuf (Vache), Porc

Hôte

  • 55
  • 4
  • 1
Lapin

Clonalité

  • 54
  • 6
Polyclonal

Conjugué

  • 44
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp AATF est non-conjugé

Application

  • 45
  • 26
  • 22
  • 12
  • 11
  • 11
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 10
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    MAGPQPLALQ LEQLLNPRPS EADPEADPEE ATAARVIDRF DEGEDGEGDF

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

    Attributs du produit

    This is a rabbit polyclonal antibody against AATF. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human AATF
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 560 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    AATF (Apoptosis Antagonizing Transcription Factor (AATF))

    Autre désignation

    AATF

    Sujet

    The AATF is a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
    Alias Symbols: DED, CHE1, CHE-1
    Protein Interaction Partner: MDM2, DAPK3, AR, HIPK2, NGDN, UBC, TSG101, LIN28A, MMS19, ZNF468, NEDD4L, WHSC1, SMAD3, EFNB3, CPD, UBD, CAND1, PIN1, SIRT7, SUMO2, CHEK2, RELA, tat, MAGED1, PCBD2, SS18L1, LZTR1, MPHOSPH6, POLR2J, MPP6, PAWR, DAZAP2, ATR, ATM, CHEK1, LDOC1, SP1, RB1, MAP
    Protein Size: 560

    Poids moléculaire

    63 kDa

    ID gène

    26574

    NCBI Accession

    NM_012138, NP_036270

    UniProt

    Q9NY61

    Pathways

    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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