ARPC2 anticorps (N-Term)
Aperçu rapide pour ARPC2 anticorps (N-Term) (ABIN406714)
Antigène
Voir toutes ARPC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MVLNVYCCFF QISDIQTMKI NQTILKEFIL VGFSVYPHVQ TFLFVVFFCL
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Homologie
- Cow: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ARPC2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ARPC2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 300 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration." dans: International journal of molecular sciences, Vol. 14, Issue 10, pp. 20220-35, (2013) (PubMed).
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- ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))
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Autre désignation
- ARPC2
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Sujet
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ARPC2 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of ARPC2, the p34 subunit, has yet to be determined. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Alias Symbols: ARC34, PNAS-139, PRO2446, p34-Arc
Protein Interaction Partner: SUMO2, UBC, ARPC5L, AARSD1, PUS1, NIF3L1, THG1L, NSUN2, SH3GLB1, LAP3, TPRKB, TNPO3, ANP32B, ACTR2, ACTR3, ARPC1B, ARPC3, ARPC4, ARPC5, TOM1L1, FUBP1, SUMO1, TPD52L2, SH3GL1, RPA2, RPA1, RANGAP1, PRKACB, PRKACA, PPP2R5D, PFDN5, PPP1R12A, MTR, METTL1, CALU
Protein Size: 300 -
Poids moléculaire
- 33 kDa
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ID gène
- 10109
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NCBI Accession
- NM_005731, NP_005722
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UniProt
- O15144
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Pathways
- Signalisation RTK, Regulation of Actin Filament Polymerization
Antigène
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