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ATP6V1B2 anticorps (N-Term)

Cet anticorps anti-ATP6V1B2 Polyclonal Lapin (ABIN503925) détecte spécifiquement ATP6V1B2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio) et Cobaye.
N° du produit ABIN503925
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour ATP6V1B2 anticorps (N-Term) (ABIN503925)

Antigène

Voir toutes ATP6V1B2 Anticorps
ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Reactivité

  • 21
  • 8
  • 8
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte

  • 16
  • 6
Lapin

Clonalité

  • 18
  • 4
Polyclonal

Conjugué

  • 22
Cet anticorp ATP6V1B2 est non-conjugé

Application

  • 20
  • 9
  • 6
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    VSRNYLSQPR LTYKTVSGVN GPLVILDHVK FPRYAEIVHL TLPDGTKRSG

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    Attributs du produit

    This is a rabbit polyclonal antibody against ATP6V1B2. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1B2
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 511 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

    Autre désignation

    ATP6V1B2

    Sujet

    ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
    Protein Interaction Partner: TCF4, UBC, PBDC1, GMPPB, GANAB, SWAP70, MSH2, JUP, MSH6, XRCC6, CRMP1, HYOU1, SEC24C, CUL2, SUPT5H, SSRP1, PDE3A, CSDE1, PAN2, FN1, SRXN1, YIF1B, UNK, ZFYVE19, TUBA1C, INTS2, TRMT1, ABCF3, ATP6V1H, CCT8, SSSCA1, TUBB4B, UBA2, USP34, ATP6V1F, ZBED1, ZPR1,
    Protein Size: 511

    Poids moléculaire

    56 kDa

    ID gène

    526

    NCBI Accession

    NM_001693, NP_001684

    UniProt

    P21281

    Pathways

    Transition Metal Ion Homeostasis, Proton Transport
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