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KCNQ2 anticorps (Middle Region)

Cet anticorps Lapin Polyclonal détecte spécifiquement KCNQ2 dans WB et IHC. Il présente une réactivité avec des échantillons de Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il a été cité dans 2+ publications.

Human kidney (KCNQ2 anticorps (Middle Region))

IHC

Host: Mouse Target Name: KCNQ2 Sample Tissue: Mouse Skeletal Muscle Antibody Dilution: 1ug/ml (KCNQ2 anticorps (Middle Region))

3 images

(2 références)

N° du produit ABIN183178

150,78 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour KCNQ2 anticorps (Middle Region) (ABIN183178)

Antigène

Voir toutes KCNQ2 Anticorps

KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Reactivité

Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp KCNQ2 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product KCNQ2 Anticorps primaire

Épitope
16

6

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region

Séquence

GNVFATSALR SLRFLQILRM IRMDRRGGTW KLLGSVVYAH SKELVTAWYI

Homologie

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit

This is a rabbit polyclonal antibody against KCNQ2. It was validated on Western Blot and immunohistochemistry.

Purification

Protein A purified

Immunogène

The immunogen is a synthetic peptide directed towards the middle region of human KCNQ2
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (N-Term) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (Middle Region) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (Middle Region) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (AA 171-220) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Roussette (Chauve-souris), Poulet, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (AA 179-228) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Roussette (Chauve-souris), Poulet, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (AA 154-203) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Roussette (Chauve-souris), Poulet, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (AA 189-238) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Roussette (Chauve-souris), Poulet, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (AA 91-150) antibody
KCNQ2 Reactivité: Rat ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (N-Term) antibody
KCNQ2 Reactivité: Rat, Humain, Souris, Chien WB Hôte: Lapin Polyclonal unconjugated

anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) (AA 254-393) antibody
KCNQ2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

Indications d'application

Optimal working dilutions should be determined experimentally by the investigator.

Commentaires

Antigen size: 393 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freeze-thaw cycles.

Stock

-20 °C

Stockage commentaire

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Zhang, Liu, Xu, Zhang, Liang, Du, Zhang: "Membrane microdomain determines the specificity of receptor-mediated modulation of Kv7/M potassium currents." dans: Neuroscience, Vol. 254, pp. 70-9, (2013) (PubMed).

Tang, Li, Xia, Jiang, Pan, Shen, Long, Zhao, Cai: "A novel mutation in KCNQ2 gene causes benign familial neonatal convulsions in a Chinese family." dans: Journal of the neurological sciences, Vol. 221, Issue 1-2, pp. 31-4, (2004) (PubMed).
Antigène

KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Autre désignation

KCNQ2

Sujet

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by the KCNQ2 gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
Alias Symbols: EBN, BFNC, EBN1, ENB1, BFNS1, EIEE7, HNSPC, KV7.2, KCNA11, KVEBN1
Protein Interaction Partner: ARIH2, KCNQ3, PRKCA, CALM3, CALM1, CALM2, KCNQ1,
Protein Size: 393

Poids moléculaire

43 kDa

ID gène

3785

NCBI Accession

NM_172109, NP_742107

UniProt

Q5VYU0