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PSMB5 anticorps (Middle Region)

Cité dans 1 publication. Cet anticorps anti-PSMB5 Polyclonal Lapin (ABIN503976) détecte spécifiquement PSMB5 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye et Saccharomyces cerevisiae.
N° du produit ABIN503976
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour PSMB5 anticorps (Middle Region) (ABIN503976)

Antigène

Voir toutes PSMB5 Anticorps
PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))

Reactivité

Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye, Saccharomyces cerevisiae

Hôte

  • 35
  • 2
  • 1
Lapin

Clonalité

  • 39
Polyclonal

Conjugué

  • 23
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PSMB5 est non-conjugé

Application

  • 25
  • 16
  • 15
  • 10
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 9
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Séquence

    IVAADSRATA GAYIASQTVK KVIEINPYLL GTMAGGAADC SFWERLLARQ

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against PSMB5. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of human PSMB5
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 263 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Antigène

    PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))

    Autre désignation

    PSMB5

    Sujet

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB5 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LMPX, MB1, MGC104214, X
    Protein Interaction Partner: UBC, AURKA, PSMD14, BMI1, PSMG3, PSMB8, PSMB7, PSMB6, PYCRL, AP3M1, RPP38, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, KIF5B, EPB41L1, CAST, XRN1, CDK20, CDKL1, PSMA2, PARK2, BAG3, IQCB1, HSP90AB1, HSP90AA1, FN1, IKBKAP, PSMA8, P
    Protein Size: 263

    Poids moléculaire

    28 kDa

    ID gène

    5693

    NCBI Accession

    NM_002797, NP_002788

    UniProt

    P28074

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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