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TAF6 anticorps (N-Term)

Il existe 1 publication pour ce produit. L’anticorps anti-TAF6 Polyclonal Lapin est utilisé pour la détection de TAF6 dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Cobaye, Boeuf (Vache), Poisson zèbre (Danio rerio) et Saccharomyces cerevisiae. Il a été validé pour WB et IHC.
N° du produit ABIN309749
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour TAF6 anticorps (N-Term) (ABIN309749)

Antigène

Voir toutes TAF6 Anticorps
TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))

Reactivité

  • 36
  • 11
  • 10
  • 8
  • 7
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Humain, Souris, Rat, Chien, Cheval, Cobaye, Boeuf (Vache), Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte

  • 30
  • 6
Lapin

Clonalité

  • 31
  • 5
Polyclonal

Conjugué

  • 27
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp TAF6 est non-conjugé

Application

  • 28
  • 15
  • 9
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 9
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    LTDEVSYRIK EIAQDALKFM HMGKRQKLTT SDIDYALKLK NVEPLYGFHA

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against TAF6. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human TAF6
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 667 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Antigène

    TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))

    Autre désignation

    TAF6

    Sujet

    TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
    Alias Symbols: DKFZp781E21155, MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85, TAFII-70, TAFII-80, TAF(II)70, TAF(II)80
    Protein Interaction Partner: SOX5, HNF4A, MED26, TRRAP, HIST3H3, UBC, TBP, AHR, APP, TAF1L, TAF3, TAF9B, TAF10, TAF9, TAF7, TAF5, TAF4, TAF2, TAF1, KMT2A, USF1, ERCC1, TAF8, KAT2A, SETD7, NR1D2, NCOR1, NFYC, NFYB, NFYA, MBD3, SIN3A, ALL1, SAP30, SMARCC2, SMARCC1, SMARCB1, SMARCA2, RB
    Protein Size: 667

    Poids moléculaire

    71 kDa

    ID gène

    6878

    NCBI Accession

    NM_139122, NP_620834

    UniProt

    A4D2B3
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