DEAF1 anticorps (C-Term)
Aperçu rapide pour DEAF1 anticorps (C-Term) (ABIN183800)
Antigène
Voir toutes DEAF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- TGCHKVNYCS TFCQRKDWKD HQHICGQSAA VTVQADEVHV AESVMEKVTV
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Homologie
- Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DEAF1
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anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 1-565) antibody
DEAF1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 133-222) antibodyDEAF1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1H8 unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (N-Term) antibodyDEAF1 Reactivité: Humain, Souris, Rat, Cobaye, Chien, Boeuf (Vache), Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 133-222) antibodyDEAF1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 3E6 unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 466-564) antibodyDEAF1 Reactivité: Humain ELISA, IP Hôte: Souris Monoclonal 6F10 unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) antibodyDEAF1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 368-400), (C-Term) antibodyDEAF1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB10698 unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 466-564) antibodyDEAF1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 6F10 unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 466-564) antibodyDEAF1 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (AA 211-310) antibodyDEAF1 Reactivité: Souris WB, ELISA, IF (p) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 565 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
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Autre désignation
- DEAF1
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Sujet
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DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alias Symbols: SPN, NUDR, ZMYND5
Protein Interaction Partner: IRF7, IRF3, CREB1, PELI1, PELI2, HRSP12, GSK3B, GSK3A, CDKN2A, PPP1CC, PPP1CA, CDC37, AIMP2, TK1, RAD23B, PIN1, HRAS, FHL1, CDKN1A, ASCC2, INTS1, LMO4, DEAF1,
Protein Size: 565 -
Poids moléculaire
- 59 kDa
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ID gène
- 10522
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NCBI Accession
- NM_021008, NP_066288
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UniProt
- O75398
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Pathways
- Tube Formation
Antigène
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