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TCEB3 anticorps (C-Term)

L’anticorps anti-TCEB3 Polyclonal Lapin est utilisé pour la détection de TCEB3 dans des échantillons de Rat, Chien et Cobaye. Il a été validé pour WB et IHC.
N° du produit ABIN184283
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour TCEB3 anticorps (C-Term) (ABIN184283)

Antigène

Voir toutes TCEB3 Anticorps
TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Reactivité

  • 41
  • 21
  • 15
  • 3
  • 2
  • 1
  • 1
Rat, Chien, Cobaye

Hôte

  • 42
  • 3
  • 2
Lapin

Clonalité

  • 45
  • 2
Polyclonal

Conjugué

  • 30
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp TCEB3 est non-conjugé

Application

  • 37
  • 23
  • 14
  • 6
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    AYDGPSTSSA HLAPVVSSTV SYDPRKPTVK KIAPMMAKTI KAFKNRFSRR

     Réactivité croisée

    Chien, Poulet, Humain, Souris, Rat (Rattus)

    Homologie

    Dog: 100%, Guinea Pig: 91%, Rat: 92%

    Attributs du produit

    This is a rabbit polyclonal antibody against TCEB3. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human TCEB3
  • Indications d'application

    WB Suggested Anti-TCEB3 Antibody Titration: 7.5 µg/mL
    Positive Control: Transfected 293T.
    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 772 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

    Autre désignation

    TCEB3

    Sujet

    Elongin A (TCEB3), which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
    Alias Symbols: EloA, SIII, TCEB3A, SIII p110
    Protein Interaction Partner: KRTAP10-3, CEP57L1, SPERT, FAM9B, KRT40, CEP70, GMCL1, HOMEZ, TRIM54, MID2, PLK4, JAKMIP2, PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, MDFI, UBC, RAD54B, MED26, ECT2, BARD1, CDK12, TCEB2, TCEB1, B
    Protein Size: 772

    Poids moléculaire

    87 kDa

    ID gène

    6924

    NCBI Accession

    NM_003198, NP_003189

    UniProt

    Q14241
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