alpha 2 Macroglobulin anticorps (C-Term)
(1 reference)Aperçu rapide pour alpha 2 Macroglobulin anticorps (C-Term) (ABIN965491)
Antigène
Voir toutes alpha 2 Macroglobulin (A2M) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Purified by antigen-specific affinity chromatography.
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Immunogène
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human A2M (Alpha-2-macroglobulin precursor)
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anti-alpha-2-Macroglobulin (A2M) (AA 616-856) antibody
A2M Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 616-856) antibodyA2M Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal C6 unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1053-1214) antibodyA2M Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1216-1467) antibodyA2M Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M Reactivité: Humain WB, IHC, ELISA, IP, IHC (p) Hôte: Chèvre Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1-1474) antibodyA2M Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 641-730) antibodyA2M Reactivité: Humain WB, ELISA, PLA Hôte: Souris Monoclonal 2B5 unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M Reactivité: Humain WB, IHC, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M Reactivité: Humain, Porc, Lapin, Chien IHC, ELISA, IP, IEP, IHC (p) Hôte: Chèvre Polyclonal unconjugated
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Indications d'application
- ELISA, Western blotting: 1µg/ml for 2hrs.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- This antibody is stored in PBS, 50% glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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: "Assembly of the endoplasmic reticulum phospholipid bilayer: the phosphatidylcholine transporter." dans: Cell, Vol. 42, Issue 1, pp. 51-60, (1985) (PubMed).
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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Autre désignation
- A2M
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Sujet
- A2M(Alpha-2-macroglobulin is able to inhibit all four classes of proteinases by a unique trapping mechanism. This protein has a peptide stretch, called the `bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
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Pathways
- Lipid Metabolism
Antigène
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