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AKAP13 anticorps

L’anticorps anti-AKAP13 Polyclonal Lapin est utilisé pour la détection de AKAP13 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).
N° du produit ABIN317612
686,15 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour AKAP13 anticorps (ABIN317612)

Antigène

Voir toutes AKAP13 Anticorps
AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))

Reactivité

  • 21
  • 3
  • 2
  • 1
Humain

Hôte

  • 14
  • 8
Lapin

Clonalité

  • 16
  • 6
Polyclonal

Conjugué

  • 22
Cet anticorp AKAP13 est non-conjugé

Application

  • 18
  • 10
  • 8
  • 6
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Specificité

    This antibody detects endogenous levels of AKAP13 Protein.(region surrounding Asp738)

    Purification

    Affinity Chromatography using epitope-specific immunogen.
  • Indications d'application

    Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))

    Autre désignation

    AKAP13

    Sujet

    AKAP13 functions as a protein kinase A (PKA)-anchoring protein and acts as an adapter protein to selectively couple G alpha-13 and Rho. It contains a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins. AKAP13 augments gene activation by the estrogen receptor and activates estrogen receptor beta by a p38 MAPK-dependent pathway. AKAP13 is involved in the signaling pathways leading to cardiomyocytes hypertrophy.Synonyms: A-kinase anchor protein 13, AKAP-Lbc, BRX, Breast cancer nuclear receptor-binding auxiliary protein, Guanine nucleotide exchange factor Lbc, HT31, Human thyroid-anchoring protein 31, LBC, Lymphoid blast crisis oncogene, Non-oncogenic Rho GTPase-specific GTP exchange factor, P47, Protein kinase A-anchoring protein 13

    ID gène

    11214

    NCBI Accession

    NP_006729

    UniProt

    Q12802

    Pathways

    Neurotrophin Signaling Pathway
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