RUNX1T1 anticorps
(1 reference)Aperçu rapide pour RUNX1T1 anticorps (ABIN965546)
Antigène
Voir toutes RUNX1T1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified by antigen-specific affinity chromatography.
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Immunogène
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AML1-MTG8(acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c)
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anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region), (N-Term) antibody
RUNX1T1 Reactivité: Humain ELISA, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 5A12 unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region) antibodyRUNX1T1 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-577) antibodyRUNX1T1 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 335-510) antibodyRUNX1T1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, IP, FACS, ICC Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 100-390) antibodyRUNX1T1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (N-Term) antibodyRUNX1T1 Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Boeuf (Vache), Porc, Poulet, Singe, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 288-337) antibodyRUNX1T1 Reactivité: Humain, Rat, Chien, Lapin, Porc, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 221-270) antibodyRUNX1T1 Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Porc, Poulet, Singe, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- ELISA, Western blotting: 1µg/ml for 2hrs.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- This antibody is stored in PBS, 50% glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." dans: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).
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- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Autre désignation
- AML1-MTG8
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Sujet
- AML1-MTG8(acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c) is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
Antigène
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