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BMPR1B anticorps (C-Term)

Il existe 3+ publications pour ce produit. L’anticorps anti-BMPR1B Polyclonal Lapin est utilisé pour la détection de BMPR1B dans des échantillons de Humain. Il a été validé pour WB et IHC (p).
N° du produit ABIN388739
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour BMPR1B anticorps (C-Term) (ABIN388739)

Antigène

Voir toutes BMPR1B Anticorps
BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Reactivité

  • 105
  • 48
  • 21
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 93
  • 12
Lapin

Clonalité

  • 95
  • 10
Polyclonal

Conjugué

  • 46
  • 9
  • 8
  • 8
  • 7
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp BMPR1B est non-conjugé

Application

  • 83
  • 56
  • 30
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB01776
  • Épitope

    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 472-502, C-Term

    Homologie

    C, M

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-502 amino acids from the C-terminal region of human BMPR1B.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Srikanth, Kim, Das, Kessler: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." dans: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).

    Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).

    Nicholls, Harrison, Gilchrist, Farnworth, Stanton: "Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function." dans: Endocrinology, Vol. 150, Issue 5, pp. 2481-90, (2009) (PubMed).

  • Antigène

    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

    Autre désignation

    BMPR1B

    Sujet

    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

    Poids moléculaire

    56930

    ID gène

    658

    NCBI Accession

    NP_001194, NP_001243721, NP_001243722, NP_001243723

    UniProt

    O00238
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