Caspase 7 anticorps (C-Term)
Aperçu rapide pour Caspase 7 anticorps (C-Term) (ABIN121893)
Antigène
Voir toutes Caspase 7 (CASP7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody recognises an epitope within the C-terminal region (CT) of Caspase-7, a 35 kDa cysteine protease, otherwise known as ICE-like Apoptotic Protease 3 (ICE-LAP3) Caspase-7.
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Purification
- Affinity Chromatography
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Immunogène
- A 16 amino acid peptide from human Caspase-7 carboxy-terminus
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Isotype
- IgG
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anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibody
CASP7 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 207-303) antibodyCASP7 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 29-198) antibodyCASP7 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 4D10B2 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 Reactivité: Humain WB, IHC, ELISA, IP, IF Hôte: Lapin Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibodyCASP7 Reactivité: Humain, Rat WB, IHC, ELISA, ICC, IF, FACS Hôte: Lapin Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 Reactivité: Humain, Souris, Rat, Singe, Porc, Chien, Lapin, Hamster, Mouton WB, IHC, IHC (p) Hôte: Souris Monoclonal 7-1-11 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) antibodyCASP7 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyKD Validated CASP7 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2090 unconjugated Recombinant Antibody
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 160-240) antibodyCASP7 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western Blot: 1.0 μg/mL - 2.0 μg/mL. Immunohistochemistry on paraffin sections: 2.0 μg/mL, this product does not require protein digestion pre-treatment of paraffin sections eg. Trypsin or pronase prior to staing, this product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skeletal muscle tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.02 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
Date de péremption
- 12 months
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Autre désignation
- Caspase-7
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Sujet
- ICE-LAP3 is a member of the ICE/Ced-3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase-7 occurs during cell death induced by the cytokine death receptors Fas/APO-1 and the receptor of tumour necrosis factor (TNFR-1), coupled with the fact that granzyme-B activated Caspase-7 cleaves the nuclear enzyme poly (ADPribose) polymerase (PARP), suggests an important role for Caspase-7 in both cytokine-mediated and Granzyme-B mediated apoptosis pathways.Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
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UniProt
- P55210
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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