CCR4 anticorps (C-Term)
Aperçu rapide pour CCR4 anticorps (C-Term) (ABIN488046)
Antigène
Voir toutes CCR4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- Recognizes C-C Chemokine Receptor 4 (CCR4/CD194).
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Immunoaffinity Chromatography.
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Immunogène
- Synthetic peptide – KLH conjugated. Epitope: C-terminal domain of Human.
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anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 201-300) antibody
CCR4 Reactivité: Humain, Rat ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) antibodyCCR4 Reactivité: Humain FACS, cELISA Hôte: Souris Monoclonal KH-4F5 unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 Reactivité: Humain, Singe ELISA, WB, FACS, IHC, IHC (p) Hôte: Chèvre Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 Reactivité: Humain, Souris, Rat ELISA, WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 309-360) antibodyCCR4 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 Reactivité: Humain, Singe ELISA, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 262-290), (C-Term) antibodyCCR4 Reactivité: Humain WB Hôte: Lapin Polyclonal RB22223 unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 17-39) antibodyCCR4 Reactivité: Humain ELISA, WB, FACS, IHC (p), IHC (fro) Hôte: Chèvre Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Middle Region) antibodyCCR4 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 180-229) antibodyCCR4 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Immunohistochemistry on Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
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- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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Autre désignation
- CD194 / CCR4
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Sujet
- Receptors for the C - C chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The C - C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR4 is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine. CCR4 mediates inflammatory responses and HIV-1 infections. It binds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derived chemokine).Synonyms: C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CMKBR4, K5-5
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ID gène
- 4887
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NCBI Accession
- NP_000901
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UniProt
- P51679
Antigène
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