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Cofilin anticorps (pSer3)

Il existe 4+ publications pour ce produit. L’anticorps anti-Cofilin Polyclonal Lapin est utilisé pour la détection de Cofilin dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et IF.

(4 références)

N° du produit ABIN362129

268,40 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 10 à 14 jours ouvrables

Aperçu rapide pour Cofilin anticorps (pSer3) (ABIN362129)

Antigène

Voir toutes Cofilin (CFL1) Anticorps

Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivité

Humain, Souris, Rat

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp Cofilin est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product CFL1 Anticorps primaire

Épitope
18

16

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11

7

7

6

5

5

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer3

Specificité

The antibody detects endogenous level of cofilin only when phosphorylated at serine 3.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène

Peptide sequence around phosphorylation site of pSer3 (M-A-S (p) -G-V) derived from Human cofilin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype

IgG
anti-Cofilin 1 (CFL1) (AA 1-166) antibody
CFL1 Reactivité: Humain WB, ELISA, IF, IHC (p) Hôte: Souris Monoclonal 1A1 unconjugated

anti-Cofilin 1 (CFL1) antibody
KO Validated CFL1 Reactivité: Humain WB, IF, ICC, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 3-161) antibody
CFL1 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (pSer3) antibody
CFL1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 70-98) antibody
CFL1 Reactivité: Humain, Souris WB, FACS Hôte: Lapin Polyclonal RB23947 unconjugated

anti-Cofilin 1 (CFL1) (AA 122-152), (C-Term) antibody
CFL1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 1-100) antibody
CFL1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 2-166) antibody
CFL1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 4-32), (N-Term) antibody
CFL1 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB20525 unconjugated

anti-Cofilin 1 (CFL1) (AA 4-144) antibody
CFL1 Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated

Indications d'application

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Huet, Rajakylä, Viita, Skarp, Crivaro, Dopie, Vartiainen: "Actin-regulated feedback loop based on Phactr4, PP1 and cofilin maintains the actin monomer pool." dans: Journal of cell science, Vol. 126, Issue Pt 2, pp. 497-507, (2013) (PubMed).

Zhang, Luo, Wan, Wu, Laski, Chen: "Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis." dans: Development (Cambridge, England), Vol. 138, Issue 3, pp. 455-64, (2011) (PubMed).

Guo, Lv, Tian, Hu, Wang, Sui, Jiang, Ruan, Nan: "Downregulation of p57 accelerates the growth and invasion of hepatocellular carcinoma." dans: Carcinogenesis, Vol. 32, Issue 12, pp. 1897-904, (2011) (PubMed).

Scott: "H. R. Morgan, Astronomer." dans: Science (New York, N.Y.), Vol. 126, Issue 3272, pp. 497, (2010) (PubMed).
Antigène

Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation

cofilin

Sujet

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Poids moléculaire

19 kDa

NCBI Accession

NP_005498

UniProt

P23528

Pathways

Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events