Cytochrome C anticorps
Aperçu rapide pour Cytochrome C anticorps (ABIN265383)
Antigène
Voir toutes Cytochrome C (CYCS) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of Cytochrome c protein (region surrounding His19).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography using epitope-specific immunogen
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Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C or (in aliquotes) at -20 °C for longer.
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Autre désignation
- Cytochrome C
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Sujet
- Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.Synonyms: CYC, CYCS
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Poids moléculaire
- approx. 15,35 kDa
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ID gène
- 54205
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NCBI Accession
- NP_061820
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UniProt
- P99999
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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