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EPHA1 anticorps (C-Term)

Cité dans 3 publications. Cet anticorps anti-EPHA1 Polyclonal Lapin (Clone RB1578) (ABIN391884) détecte spécifiquement EPHA1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.
N° du produit ABIN391884
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour EPHA1 anticorps (C-Term) (ABIN391884)

Antigène

Voir toutes EPHA1 Anticorps
EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Reactivité

  • 90
  • 42
  • 8
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Humain

Hôte

  • 95
  • 8
Lapin

Clonalité

  • 96
  • 8
Polyclonal

Conjugué

  • 53
  • 8
  • 8
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp EPHA1 est non-conjugé

Application

  • 66
  • 48
  • 38
  • 14
  • 13
  • 13
  • 9
  • 8
  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB1578
  • Épitope

    • 15
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 913-943, C-Term

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This EphA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 913-943 amino acids from the C-terminal region of human EphA1.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Wang, Hu, Tian, Zhou, Zhou, Wang: "Expression of EphA2 protein is positively associated with age, tumor size and Fuhrman nuclear grade in clear cell renal cell carcinomas." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 13374-80, (2016) (PubMed).

    Wang, Liu, Cao, Zhang, Xu, Xu, Wang: "Expression of the EphA1 protein is associated with Fuhrman nuclear grade in clear cell renal cell carcinomas." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6821-7, (2015) (PubMed).

    Dong, Wang, Sheng, Li, Ma, Wang, Zhang, Lu, Hu, Sugimura, Zhou: "Downregulation of EphA1 in colorectal carcinomas correlates with invasion and metastasis." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 1, pp. 151-60, (2008) (PubMed).

  • Antigène

    EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

    Autre désignation

    EphA1

    Sujet

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

    Poids moléculaire

    108127

    ID gène

    2041

    NCBI Accession

    NP_005223

    UniProt

    P21709
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