ErbB2/Her2 anticorps
(5 références)Aperçu rapide pour ErbB2/Her2 anticorps (ABIN966277)
Antigène
Voir toutes ErbB2/Her2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- HER2 (Ab-1221/1222) antibody detects endogenous levels of total HER2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized non-phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 1221/1222 (N-L-YP-YP -W).
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat, Chien, Singe, Cheval, Porc, Lapin, Boeuf (Vache), Hamster, Avian, Cat, Poulet, Âne, Chévre, Cobaye, Mouton WB, IHC (p), IHC (fro) Hôte: Chèvre Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1248) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr877) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1112) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 Reactivité: Humain WB, IF, ELISA, IHC (p), PLA Hôte: Souris Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reactivité: Humain IHC, IF, FACS Hôte: Souris Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reactivité: Humain IHC Hôte: Souris Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 Reactivité: Humain, Souris WB, IHC, FACS, IP, ICC Hôte: Lapin Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1196) antibodyErbB2/Her2 Reactivité: Humain WB, IF, DB Hôte: Lapin Polyclonal RB40085 unconjugated
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Indications d'application
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WB: 1:500~1:1000
IHC: 1:50~1:100. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100ug/100ul.
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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: "Memo mediates ErbB2-driven cell motility." dans: Nature cell biology, Vol. 6, Issue 6, pp. 515-22, (2004) (PubMed).
: "ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner." dans: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38486-93, (2002) (PubMed).
: "Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2." dans: Cancer research, Vol. 60, Issue 13, pp. 3384-8, (2000) (PubMed).
: "The duration of phorbol-inducible ErbB2 tyrosine dephosphorylation parallels that of receptor endocytosis rather than threonine-686 phosphorylation: implications for the physiological role of protein kinase C in growth factor receptor signalling." dans: Carcinogenesis, Vol. 19, Issue 11, pp. 2013-9, (1998) (PubMed).
: "Adjacent carboxyterminal tyrosine phosphorylation events identify functionally distinct ErbB2 receptor subsets: implications for molecular diagnostics." dans: Experimental cell research, Vol. 241, Issue 2, pp. 467-75, (1998) (PubMed).
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Autre désignation
- HER2
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
Antigène
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