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FOXO1 anticorps (pSer256)

Il existe 3+ publications pour ce produit. L’anticorps anti-FOXO1 Polyclonal Lapin est utilisé pour la détection de FOXO1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et IF.

(3 références)

N° du produit ABIN362087

268,40 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 10 à 14 jours ouvrables

Aperçu rapide pour FOXO1 anticorps (pSer256) (ABIN362087)

Antigène

Voir toutes FOXO1 Anticorps

FOXO1 (Forkhead Box O1 (FOXO1))

Reactivité

Humain, Souris, Rat

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp FOXO1 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product FOXO1 Anticorps primaire

Épitope
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pSer256

Specificité

The antibody detects endogenous level of FKHR only when phosphorylated at serine 256.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène

Peptide sequence around phosphorylation site of pSer256 (A-A-S (p) -M-D) derived from Human FKHR. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype

IgG
anti-Forkhead Box O1 (FOXO1) (AA 165-270) antibody
FOXO1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Poulet WB, ELISA, IF (p), IHC (p), FACS Hôte: Lapin Polyclonal unconjugated

anti-Forkhead Box O1 (FOXO1) (AA 333-557) antibody
FOXO1 Reactivité: Humain WB, IHC, IF, FACS Hôte: Lapin Polyclonal unconjugated

anti-Forkhead Box O1 (FOXO1) antibody
FOXO1 Reactivité: Humain, Souris WB, IHC, ELISA, ICC Hôte: Souris Monoclonal 3B6 unconjugated

anti-Forkhead Box O1 (FOXO1) antibody
FOXO1 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Souris Monoclonal 3B6 unconjugated

anti-Forkhead Box O1 (FOXO1) antibody
KD Validated FOXO1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB850 unconjugated Recombinant Antibody

anti-Forkhead Box O1 (FOXO1) (AA 556-655) antibody
FOXO1 Reactivité: Humain WB, ELISA, IF, PLA Hôte: Souris Monoclonal 4E9 unconjugated

anti-Forkhead Box O1 (FOXO1) (pSer256) antibody
FOXO1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Forkhead Box O1 (FOXO1) (AA 452-555) antibody
FOXO1 Reactivité: Humain WB, ELISA, IF, IHC (p) Hôte: Souris Monoclonal 3A10 unconjugated

anti-Forkhead Box O1 (FOXO1) antibody
FOXO1 Reactivité: Humain, Souris WB, IF, IHC (p), EIA Hôte: Souris Monoclonal 3B6 unconjugated

anti-Forkhead Box O1 (FOXO1) (AA 222-469) antibody
FOXO1 Reactivité: Souris WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated

Indications d'application

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Pierce, Podlutskaya, Halloran, Hussong, Lin, Burbank, Hart, Galvan: "Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease." dans: Journal of neurochemistry, Vol. 124, Issue 6, pp. 880-93, (2013) (PubMed).

Ma, Li, Wang, Gong, Zhang, Li, Ji, Liu, Chen, Xiang: "Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways." dans: Regulatory peptides, Vol. 181, pp. 9-16, (2013) (PubMed).

Zhan, Wang, Li, Xu, Sun, Xu: "Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats." dans: Journal of neurochemistry, Vol. 114, Issue 3, pp. 897-908, (2010) (PubMed).
Antigène

FOXO1 (Forkhead Box O1 (FOXO1))

Autre désignation

FKHR

Sujet

Transcription factor.

Poids moléculaire

78-82 kDa

NCBI Accession

NP_002006

UniProt

Q12778

Pathways

Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling