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GRP78 anticorps (C-Term)

Cité dans 1 publication. Cet anticorps anti-GRP78 Polyclonal Lapin (Clone RB20814) (ABIN651231) détecte spécifiquement GRP78 dans WB, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain.

HS Antibody (C-term) (ABIN651231 and ABIN2840143) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). (GRP78 anticorps (C-Term))

FACS

HS Antibody (C-term) (ABIN651231 and ABIN2840143) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (GRP78 anticorps (C-Term))

IHC (p)

3 images

(1 reference)

N° du produit ABIN651231

434,77 €

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Destination: France

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Aperçu rapide pour GRP78 anticorps (C-Term) (ABIN651231)

Antigène

Voir toutes GRP78 (HSPA5) Anticorps

GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp GRP78 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone

RB20814

Discover our top product HSPA5 Anticorps primaire

Épitope
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AA 541-568, C-Term

Homologie

B, Ha, M, Pig, Rat, X

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-568 amino acids from the C-terminal region of human HSPA5.

Isotype

Ig Fraction
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody
HSPA5 Reactivité: Humain, Souris WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB1768 unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (Internal Region) antibody
HSPA5 Reactivité: Humain, Rat, Souris WB, ICC, IF, IP, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 550-650) antibody
HSPA5 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (PE)
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal PE

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (FITC)
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal FITC

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (APC)
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal APC

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (HRP)
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal HRP

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (Atto 594)
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal Atto 594

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (Atto 488)
HSPA5 Reactivité: Rat WB, IHC, ICC, IF, IP Hôte: Lapin Polyclonal Atto 488

Indications d'application

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Haenig, Atias, Taylor, Mazza, Schaefer, Russ, Riechers, Jain, Coughlin, Fontaine, Freibaum, Brusendorf, Zenkner, Porras, Stroedicke, Schnoegl, Arnsburg, Boeddrich, Pigazzini, Heutink, Taylor et al.: "Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. ..." dans: Cell reports, Vol. 32, Issue 7, pp. 108050, (2020) (PubMed).
Antigène

GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Autre désignation

HSPA5

Sujet

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.

Poids moléculaire

72333

ID gène

3309

NCBI Accession

NP_005338

UniProt

P11021

Pathways

Thyroid Hormone Synthesis, ER-Nucleus Signaling