IKBKB anticorps (Middle Region)
(5 références)Aperçu rapide pour IKBKB anticorps (Middle Region) (ABIN966380)
Antigène
Voir toutes IKBKB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Immunogène
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of human IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)
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anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 630-730) antibody
IKBKB Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (C-Term) antibodyIKBKB Reactivité: Humain WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (pTyr199) antibodyIKBKB Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibodyIKBKB Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB2161 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 3-120) antibodyIKBKB Reactivité: Humain WB, ELISA, PLA Hôte: Souris Monoclonal 1A3 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibodyIKBKB Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibodyIKBKB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 3-120) antibodyIKBKB Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 3C12 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibodyIKBKB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Monoclonal 3E1 unconjugated Recombinant Antibody
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 395-588) antibodyIKBKB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
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Restrictions
- For Research Use only
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Stock
- 4 °C
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: "IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes." dans: Gene, Vol. 222, Issue 1, pp. 31-40, (1999) (PubMed).
: "The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation." dans: The EMBO journal, Vol. 18, Issue 11, pp. 3044-53, (1999) (PubMed).
: "Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization." dans: Cytogenetics and cell genetics, Vol. 82, Issue 1-2, pp. 32-3, (1998) (PubMed).
: "Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase." dans: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7336-43, (1998) (PubMed).
: "IKAP is a scaffold protein of the IkappaB kinase complex." dans: Nature, Vol. 395, Issue 6699, pp. 292-6, (1998) (PubMed).
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- IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
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Autre désignation
- IKBKB
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Sujet
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IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta) acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. IKBKB also phosphorylates NCOA3. Component of the I-kappa-B-kinase (IKK) core complex consists of CHUK, IKBKB and IKBKG, probably four alpha/CHUK-beta/IKBKB dimers are associated with four gamma/IKBKG subunits. The IKK core complex seems to associate with regulatory or adapter proteins to form a IKK-signalosome holo-complex. Part of a complex composed of NCOA2, NCOA3, CHUK/IKKA, IKBKB, IKBKG and CREBBP. Part of a 70-90 kDa complex at least consisting of CHUK/IKKA, IKBKB, NFKBIA, RELA, IKBKAP and MAP3K14.
Synonyms: IKKB -
Pathways
- Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
Antigène
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