KLLN anticorps (C-Term)
Cet anticorps Lapin Polyclonal détecte spécifiquement KLLN dans WB. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.
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(3 références)
N° du produit ABIN655558
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination:
France
Envoi sous 14 à 17 jours ouvrables
Aperçu rapide pour KLLN anticorps (C-Term) (ABIN655558)
Antigène
Voir toutes KLLN Anticorps
KLLN
(Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
Reactivité
Humain
Hôte
Lapin
Clonalité
Polyclonal
Conjugué
Cet anticorp KLLN est non-conjugé
Application
Western Blotting (WB)
Clone
RB29503
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Épitope
- AA 136-163, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." dans: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).
: "Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation." dans: Molecular cancer therapeutics, Vol. 13, Issue 2, pp. 517-27, (2014) (PubMed).
: "Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas." dans: Human molecular genetics, Vol. 22, Issue 11, pp. 2263-72, (2013) (PubMed).
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- KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
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Autre désignation
- KILLIN
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Sujet
- DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
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Poids moléculaire
- 19958
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ID gène
- 100144748
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NCBI Accession
- NP_001119521
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UniProt
- B2CW77
Antigène
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