Il existe 1 publication pour ce produit.
L’anticorps anti-LATS2 Polyclonal Lapin est utilisé pour la détection de LATS2 dans des échantillons de Humain. Il a été validé pour IHC (p).
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This LATS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the Central region of human LATS2.
LATS2
Reactivité: Poisson zèbre (Danio rerio)
Hôte: Lapin
Polyclonal
FITC
Indications d'application
IHC-P: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Yamashita, Yamamoto, Mimori, Nishida, Takahashi, Haraguchi, Tanaka, Shibata, Sekimoto, Ishii, Doki, Mori: "MicroRNA-372 is associated with poor prognosis in colorectal cancer." dans: Oncology, Vol. 82, Issue 4, pp. 205-12, (2012) (PubMed).
Antigène
LATS2
(LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
Autre désignation
LATS2
Sujet
LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.