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LGR5 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement LGR5 dans WB. Il présente une réactivité avec des échantillons de Souris. Il a été cité dans 4+ publications.
N° du produit ABIN389215
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour LGR5 anticorps (N-Term) (ABIN389215)

Antigène

Voir toutes LGR5 Anticorps
LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivité

  • 115
  • 68
  • 53
  • 1
  • 1
Souris

Hôte

  • 92
  • 20
  • 3
  • 1
Lapin

Clonalité

  • 72
  • 44
Polyclonal

Conjugué

  • 57
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Cet anticorp LGR5 est non-conjugé

Application

  • 80
  • 51
  • 24
  • 21
  • 18
  • 16
  • 15
  • 14
  • 13
  • 9
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB14764
  • Épitope

    • 17
    • 15
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 238-270, N-Term

    Homologie

    H

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This LGR5/GPR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-270 amino acids from the N-terminal region of human LGR5/GPR49.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Usui, Sakurai, Enjoji, Kawasaki, Umata, Ohama, Fujiwara, Yabe, Tsuji, Yamawaki, Hazama, Takenouchi, Nakajima, Tsunedomi, Suzuki, Nagano, Sato: "Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment." dans: Stem cells international, Vol. 2016, pp. 7053872, (2017) (PubMed).

    Fender, Nutter, Bertrand, Sigounas: "Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer." dans: Journal of cellular biochemistry, (2015) (PubMed).

    Jardé, Kass, Staples, Lescesen, Carne, Oliva, McMurrick, Abud: "ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0138336, (2015) (PubMed).

    Kanwar, Yu, Nautiyal, Patel, Majumdar: "The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres." dans: Molecular cancer, Vol. 9, pp. 212, (2010) (PubMed).

  • Antigène

    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

    Autre désignation

    LGR5/GPR49

    Sujet

    LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.

    Poids moléculaire

    99998

    ID gène

    8549

    NCBI Accession

    NP_001264155, NP_003658

    UniProt

    O75473

    Pathways

    Signalisation WNT
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