LTA anticorps
Aperçu rapide pour LTA anticorps (ABIN272216)
Antigène
Voir toutes LTA AnticorpsHôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of LT-beta protein. (region surrounding Val211)
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Pureté
- > 95 % pure by SDS-PAGE
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anti-Lymphotoxin-alpha (LTA) (AA 49-202) antibody
LTA Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 36-205) antibodyLTA Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal C4 unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 46-72) antibodyLTA Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21239 unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 1-205) antibodyLTA Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (Internal Region) antibodyLTA Reactivité: Humain, Rat, Souris WB, IHC, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 36-205) antibodyLTA Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 35-191) antibodyLTA Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (Middle Region) antibodyLTA Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) antibodyLTA Reactivité: Humain ELISA, Neut, FACS, SPR Hôte: Lapin Chimeric 3F12-2D3 unconjugated Recombinant Antibody
anti-Lymphotoxin-alpha (LTA) (AA 58-205) antibody (DYKDDDDK Tag,His tag)LTA Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2D11 DYKDDDDK Tag,His tag
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Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- DO NOT FREEZE!
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- LTA (Lymphotoxin-alpha (LTA))
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Autre désignation
- TNF-beta / Lymphotoxin-alpha
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Classe de substances
- Chemical
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Sujet
- Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha, also known as TNF-beta) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-beta (lymphotaxin-beta or tumor necrosis factor C) is a type II membrane protein with significant homology to TNF, LT-alpha, and the ligand for the CD40 receptor. LT-alpha is present on the surface of activated T, B, and LAK cells as a complex with the 33 kda glycoprotein, LT-beta. LT-beta, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-alpha to the cell surface. A TNF receptor-related protein, the LT-beta receptor (also known as TNFC receptor), is the human receptor for the LT-alpha/LT-beta heterotrimer. There are two LT-beta isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas. The gene which encodes LT-beta maps to the major histocompatibility complex region on human chromosome 6p21.3.Synonyms: LT-alpha, LTA, TNFB, TNFSF1, Tumor necrosis factor ligand superfamily member 1
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Poids moléculaire
- approx. 22 kDa
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ID gène
- 4049
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NCBI Accession
- NP_000586
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UniProt
- P01374
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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