MARCH1 anticorps (N-Term)
Aperçu rapide pour MARCH1 anticorps (N-Term) (ABIN405536)
Antigène
Voir toutes MARCH1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LQASSPTTGT APRSQSRLSV CPSTQDICRI CHCEGDEESP LITPCRCTGT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MARCH1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH1
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anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (C-Term) antibody
MARCH1 Reactivité: Humain, Souris, Rat ELISA, WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (Center) antibodyMARCH1 Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (AA 1-99) antibodyMARCH1 Reactivité: Humain ELISA, WB Hôte: Souris Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (AA 1-99) antibodyMARCH1 Reactivité: Humain ELISA Hôte: Souris Monoclonal 3D2 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (AA 36-85) antibodyMARCH1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Roussette (Chauve-souris), Poulet, Singe WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 272 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
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Autre désignation
- MARCH1
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Sujet
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MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: DKFZp564M1682, FLJ20668, MARCH-I, RNF171
Protein Interaction Partner: TNFRSF10A, UBE2H, UBE2D1, CDC34, TFRC, UBC, HLA-DRB1, HLA-DRA, PPP2R1B, PPP2R1A, CD86,
Protein Size: 272 -
Poids moléculaire
- 31 kDa
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ID gène
- 55016
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NCBI Accession
- NM_017923, NP_060393
Antigène
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