Myeloperoxidase anticorps
Aperçu rapide pour Myeloperoxidase anticorps (ABIN191711)
Antigène
Voir toutes Myeloperoxidase (MPO) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Purification
- Protein G Chromatography
-
Immunogène
- Human Myeloperoxidase
-
-
anti-Myeloperoxidase (MPO) (AA 406-745) antibody
MPO Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 134-263) antibodyMPO Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 646-745) antibodyMPO Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 3E11 unconjugated
anti-Myeloperoxidase (MPO) (AA 50-310) antibodyMPO Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 406-745) antibodyMPO Reactivité: Humain WB, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 678-745) antibodyMPO Reactivité: Humain, Souris, Rat ELISA, ICC, FACS, IHC (p), IHC (fro), IF (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 253-718) antibodyMPO Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) antibodyMPO Reactivité: Humain IHC Hôte: Souris Monoclonal 692M unconjugated
anti-Myeloperoxidase (MPO) (AA 714-728), (C-Term) antibodyMPO Reactivité: Humain, Souris, Rat WB, IHC, FACS, IF Hôte: Lapin Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 165-278) antibodyMPO Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal C3 unconjugated
-
-
Indications d'application
-
ELISA. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Reconstitution
- Restore in aqua bidest to 1 mg/mL.
-
Buffer
- TRIS, pH 7.4
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store lyophilized at 2-8 °C and reconstituted at -20 °C.
-
-
- Myeloperoxidase (MPO)
-
Autre désignation
- Myeloperoxidase
-
Sujet
- Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and two unglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers.Synonyms: MPO
-
ID gène
- 9606
-
UniProt
- P05164
-
Pathways
- Chromatin Binding
Antigène
-
