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OAS1 anticorps (C-Term)

Il existe 7+ publications pour ce produit. L’anticorps anti-OAS1 Polyclonal Lapin est utilisé pour la détection de OAS1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC (p).

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with OAS1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (OAS1 anticorps (C-Term))

IHC (p)

All lanes : Anti-OAS1 Antibody (C-term) at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Human kidney lysate Lysates/proteins at 20 μg per lane. (OAS1 anticorps (C-Term))

3 images

(7 références)

N° du produit ABIN390164

467,50 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour OAS1 anticorps (C-Term) (ABIN390164)

Antigène

Voir toutes OAS1 Anticorps

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Reactivité

Humain, Souris

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp OAS1 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB1937

Discover our top product OAS1 Anticorps primaire

Épitope
6

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2

1

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1
AA 302-330, C-Term

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This OAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human OAS1.

Isotype

Ig Fraction
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 139-358) antibody
OAS1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (Middle Region) antibody
OAS1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 Reactivité: Humain WB, IHC Hôte: Souris Monoclonal C5 unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) antibody
OAS1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) antibody
OAS1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 296-395) antibody
OAS1 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 324-373) antibody
OAS1 Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibody
OAS1 Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (N-Term) antibody
OAS1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Gielen, Johnston, Edwards: "Azithromycin induces anti-viral responses in bronchial epithelial cells." dans: The European respiratory journal, Vol. 36, Issue 3, pp. 646-54, (2010) (PubMed).

Kriegs, Bürckstümmer, Himmelsbach, Bruns, Frelin, Ahlén, Sällberg, Hildt: "The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28343-51, (2009) (PubMed).

Wang, Ghosh, Baigude, Yang, Qiu, Xia, Zhou, Rana, Xu: "Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression." dans: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15845-52, (2008) (PubMed).

Han, Townsend, Jha, Paranjape, Silverman, Barton: "A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L." dans: Journal of virology, Vol. 81, Issue 11, pp. 5561-72, (2007) (PubMed).

Alimirah, Chen, Davis, Choubey: "IFI16 in human prostate cancer." dans: Molecular cancer research : MCR, Vol. 5, Issue 3, pp. 251-9, (2007) (PubMed).

van den Pol, Robek, Ghosh, Ozduman, Bandi, Whim, Wollmann: "Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain." dans: Journal of virology, Vol. 81, Issue 1, pp. 332-48, (2006) (PubMed).

Lee, Wu, Lee, Chuang, Katakura, Liu, Chan, Tawatao, Chung, Shen, Cottam, Lai, Raz, Carson: "Activation of anti-hepatitis C virus responses via Toll-like receptor 7." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 6, pp. 1828-33, (2006) (PubMed).
Antigène

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Autre désignation

OAS1

Sujet

OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.

Poids moléculaire

46029

ID gène

4938

NCBI Accession

NP_001027581, NP_002525, NP_058132

UniProt

P00973

Pathways

Hepatitis C