PARP6 anticorps (C-Term)
Aperçu rapide pour PARP6 anticorps (C-Term) (ABIN390249)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 553-583, C-Term
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Homologie
- M
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-583 amino acids from the C-terminal region of human Parp6.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))
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Autre désignation
- Parp6
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Sujet
- Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
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Poids moléculaire
- 71115
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ID gène
- 56965
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NCBI Accession
- NP_064599
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UniProt
- Q2NL67
Antigène
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