PDE9A anticorps
Aperçu rapide pour PDE9A anticorps (ABIN302526)
Antigène
Voir toutes PDE9A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects Phosphodiesterase 9A (PDE9A) at internal domain.
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Purification
- Immunoaffinity chromatography
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Immunogène
- PDE9A antibody was raised against synthetic peptide from human PDE9A.
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anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibody
PDE9A Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 434-533) antibodyPDE9A Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 1E1 unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 426-533) antibodyPDE9A Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibodyPDE9A Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 136-185) antibodyPDE9A Reactivité: Humain, Chien WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- PDE9A (phosphodiesterase 9A (PDE9A))
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Autre désignation
- PDE9A
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Sujet
- Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.Synonyms: 5'-cyclic phosphodiesterase 9A, HSPDE9A2, High affinity cGMP-specific 3', Phosphodiesterase 9A, Phosphodiesterase PDE9A21
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ID gène
- 5152
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NCBI Accession
- NP_001001567
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UniProt
- O76083
Antigène
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