Phospholipase C gamma 2 anticorps (pTyr753)
Aperçu rapide pour Phospholipase C gamma 2 anticorps (pTyr753) (ABIN362187)
Antigène
Voir toutes Phospholipase C gamma 2 (PLCG2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr753
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Specificité
- The antibody detects endogenous level of PLCg2 only when phosphorylated at tyrosine 753.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
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Immunogène
- Peptide sequence around phosphorylation site of pTyr753 (S-L-Y (p) -D-V) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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Isotype
- IgG
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anti-Phospholipase C gamma 2 (PLCG2) (AA 1-300) antibody
PLCG2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 826-985) antibodyPLCG2 Reactivité: Humain ELISA, FACS, ICC Hôte: Souris Monoclonal 2D9E8 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1201-1258) antibodyPLCG2 Reactivité: Humain WB, IHC, ELISA, IF, FACS, ICC Hôte: Lapin Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 Reactivité: Humain WB, PLA Hôte: Souris Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibodyPLCG2 Reactivité: Humain, Rat, Souris WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibodyPLCG2 Reactivité: Humain WB, ELISA, FACS, ICC Hôte: Souris Monoclonal 3A8B6 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 826-985) antibodyPLCG2 Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 1E10C11 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 930-1152) antibodyPLCG2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Phospholipase C gamma 2 (PLCG2)
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Autre désignation
- PLCgamma2
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Sujet
- The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
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Poids moléculaire
- 150 kDa
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NCBI Accession
- NP_002652
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UniProt
- P16885
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Pathways
- Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Antigène
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