PRKAA1 anticorps (AA 485-489)
(1 reference)Aperçu rapide pour PRKAA1 anticorps (AA 485-489) (ABIN362721)
Antigène
Voir toutes PRKAA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 485-489
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Specificité
- The antibody detects endogenous level of total AMPKa1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogène
- Peptide sequence around AA 485-489 (S-G-S-V-S) derived from Human AMPKa1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 1-300) antibody
PRKAA1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 28-257) antibodyPRKAA1 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) antibodyPRKAA1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, ICC, FACS Hôte: Souris Monoclonal 2B7 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 451-550) antibodyPRKAA1 Reactivité: Humain WB, ELISA, IF, IHC (p) Hôte: Souris Monoclonal 4D8 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 351-450) antibodyPRKAA1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), FACS Hôte: Lapin Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 351-450) antibodyPRKAA1 Reactivité: Humain, Souris, Rat, Porc, Mouton WB, IHC (p), FACS, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) antibodyKD Validated PRKAA1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB2685 unconjugated Recombinant Antibody
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 451-550) antibodyPRKAA1 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 4D9 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pSer487) antibodyPRKAA1 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 325-543), (Catalytic Subunit) antibodyPRKAA1 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Construction of adiponectin-encoding plasmid DNA and overexpression in mice in vivo." dans: Gene, Vol. 502, Issue 2, pp. 87-93, (2012) (PubMed).
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- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
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Autre désignation
- AMPKalpha1
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Sujet
- Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
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Poids moléculaire
- 63 kDa
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NCBI Accession
- NP_006242
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UniProt
- P54646
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Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
Antigène
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