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Paxillin anticorps (pTyr31)

Name: Paxillin anticorps (pTyr31)
SKU: ABIN498711
Availability: InStock

Cet anticorps anti-Paxillin Polyclonal Lapin (ABIN498711) détecte spécifiquement Paxillin dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Western blot (WB) analyzes of p-Paxillin (pTyr31) antibody in extracts from HeLa TNF cells. (Paxillin anticorps (pTyr31))

Immunohistochemistry (IHC) analyzes of p-Paxillin (pTyr31) antibody in paraffin-embedded human tonsil tissue. (Paxillin anticorps (pTyr31))

IHC (p)

2 images

N° du produit ABIN498711

655,38 €

Plus frais de livraison 40,00 € et TVA

0.1 mg

Destination: France

Envoi sous 17 jours ouvrables

Aperçu rapide pour Paxillin anticorps (pTyr31) (ABIN498711)

Antigène

Voir toutes Paxillin (PXN) Anticorps

Paxillin (PXN)

Reactivité

Humain, Souris, Rat

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp Paxillin est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product PXN Anticorps primaire

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pTyr31

Specificité

This antibody detects endogenous levels of p-Paxillin protein, only when phosphorylated at Tyr31.

Réactivité croisée (Details)

Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification

Affinity chromatography

Pureté

> 95 % by SDS-PAGE
anti-Paxillin (PXN) (AA 347-578) antibody
PXN Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) (AA 201-461) antibody
PXN Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) (AA 327-568) antibody
PXN Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) (AA 456-472) antibody
PXN Reactivité: Humain, Souris, Rat WB, ICC, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) (AA 9-570) antibody
PXN Reactivité: Humain, Souris, Rat WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) antibody
KD Validated PXN Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB2690 unconjugated Recombinant Antibody

anti-Paxillin (PXN) (AA 1-557) antibody
PXN Reactivité: Humain, Souris, Rat, Poulet, Chien WB, IHC, IF, IP Hôte: Souris Monoclonal 165-Paxillin unconjugated

anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody
PXN Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC, FACS, IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Paxillin (PXN) (AA 94-125) antibody
PXN Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB15414 unconjugated

Indications d'application

Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

1,0 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freezing and thawing.

Stock

4 °C/-20 °C

Stockage commentaire

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène

Paxillin (PXN)

Autre désignation

Paxillin / PXN

Sujet

The effects of some oncogenes, growth factors and neuropeptides are mediated by tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin cytoskeletal proteins. A rapid increase in tyrosine phosphorylation of paxillin, FAK and Crk-associated substrate (CAS) are prominent early events triggered by many G protein-coupled receptors. In addition to G protein-coupled receptors, Angiotensin IV (Ang IV), protein kinase C and other proteins can also mediate the tyrosine phosphorylation of paxillin. Paxillin must bind FAK for maximal phosphorylation in response to cell adhesion. FAK may function to direct tyrosine phosphorylation of paxillin in the process of transformation by the Src oncogene.Synonyms: FLJ16691

Poids moléculaire

approx. 68 kDa

ID gène

5829

NCBI Accession

NP_001074324

UniProt

P49023

Pathways

Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling