NF-kB p65 anticorps
Aperçu rapide pour NF-kB p65 anticorps (ABIN272045)
Antigène
Voir toutes NF-kB p65 (NFkBP65) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of NFkappaB-p65 protein. (region surrounding Ala499)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography using epitope-specific immunogen
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Pureté
- > 95 % (by SDS-PAGE)
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anti-Nuclear Factor-kB p65 (NFkBP65) (AA 51-100) antibody
NFkBP65 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Poulet WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pSer536) antibodyNFkBP65 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet WB, ELISA, IHC (p), FACS Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pSer536) antibodyNFkBP65 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) antibodyNFkBP65 Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio) WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (Center) antibodyNFkBP65 Reactivité: Humain, Souris WB, IF, IHC (p), ICC, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 10-37), (N-Term) antibodyNFkBP65 Reactivité: Humain, Souris WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB20786 unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 19-306) antibodyNFkBP65 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (acLys314), (acLys315) antibodyNFkBP65 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 50-180) antibodyNFkBP65 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pThr435) antibodyNFkBP65 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1: 40000approx. 1: 60000. Western blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- DO NOT FREEZE!
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
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Autre désignation
- RELA / NF-kB p65
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Sujet
- P65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory protein known as IkB. An impressive variety of stimuli (tumor necrosis factor, interleukin 1, T cell activation signals, bacterial endotoxins, viral transforming proteins, certain growth factors and reactive oxygen intermediates) lead to the rapid nuclear accumulation of NFkB by the induced phosphorylation and subsequent degradation of IkB. In the nucleus, NFkB regulates genes encoding cytokines, cytokine receptors, cell adhesion molecules, proteins involved in coagulation and genes involved in cell growth control. Additionally, NFkB is thought to be an important transcriptional regulator for HIV. Growing evidence indicates that the dysregulation of NFkB may be key to a number of diseases including arthritis and other inflammatory diseases, Alzheimer's disease, atherosclerosis and cancer.Synonyms: NF kappa B p65, NFKB3, NFkB p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Rel A, Transcription factor p65
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Poids moléculaire
- approx. 60, 75 kDa
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ID gène
- 5970
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NCBI Accession
- NP_001138610
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UniProt
- Q04206
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
Antigène
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