MSK1 anticorps (AA 374-378)
Aperçu rapide pour MSK1 anticorps (AA 374-378) (ABIN362837)
Antigène
Voir toutes MSK1 (RPS6KA5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 374-378
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Specificité
- The antibody detects endogenous level of total MSK1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Peptide sequence around AA 374-378 (G-Y-S-F-V) derived from Human MSK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 540-665) antibody
RPS6KA5 Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 271-370) antibodyRPS6KA5 Reactivité: Humain WB, ELISA, IF, PLA Hôte: Souris Monoclonal 2B11 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 224-367) antibodyRPS6KA5 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 1-802) antibodyRPS6KA5 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) antibodyRPS6KA5 Reactivité: Humain ELISA, IHC, IHC (p) Hôte: Souris Monoclonal 1G7 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer376) antibodyKO Validated RPS6KA5 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2625 unconjugated Recombinant Antibody
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (Ser212) antibodyRPS6KA5 Reactivité: Humain, Souris WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (Internal Region) antibodyRPS6KA5 Reactivité: Humain, Souris WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer376) antibodyRPS6KA5 Reactivité: Humain, Souris, Rat WB, IF (cc), IHC (p) Hôte: Lapin Monoclonal 11A1 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer212) antibodyRPS6KA5 Reactivité: Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Western blotting: 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
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Autre désignation
- MSK1
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Sujet
- Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).
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Poids moléculaire
- 90 kDa
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NCBI Accession
- NP_004746
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UniProt
- O75582
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Pathways
- Signalisation MAPK, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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