SHPRH anticorps (N-Term)
(3 références)Aperçu rapide pour SHPRH anticorps (N-Term) (ABIN967027)
Antigène
Voir toutes SHPRH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Immunogène
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human SHPRH (E3 ubiquitin-protein ligase SHPRH )
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anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 1362-1512) antibody
SHPRH Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) antibodySHPRH Reactivité: Humain, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 1560-1659) antibodySHPRH Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (N-Term) antibodySHPRH Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 251-300) antibodySHPRH Reactivité: Humain, Souris, Rat, Cheval, Porc, Lapin, Roussette (Chauve-souris), Hamster WB Hôte: Lapin Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 1-100), (AA 1500-1600) antibodySHPRH Reactivité: Humain WB Hôte: Souris Monoclonal 6D9 unconjugated
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Restrictions
- For Research Use only
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Stock
- 4 °C
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: "Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 34, pp. 12411-6, (2008) (PubMed).
: "Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination." dans: The Journal of cell biology, Vol. 175, Issue 5, pp. 703-8, (2006) (PubMed).
: "Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region." dans: Genomics, Vol. 82, Issue 2, pp. 153-61, (2003) (PubMed).
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- SHPRH (SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH))
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Autre désignation
- SHPRH
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Sujet
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SHPRH (E3 ubiquitin-protein ligase SHPRH ) involved in DNA repair. Upon genotoxic stress, SHPRH accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of noncanonical poly-ubiquitin chains linked through 'Lys-63'. SHPRH interacts with HLTF, PCNA, UBE2N and RAD18. The RING finger mediates E3 ubiquitin ligase activity. SHPRH belongs to the SNF2/RAD54 helicase family. SHPRH contains 1 helicase ATP-binding domain, 1 helicase C-terminal domain, 1 histone H1 domain, 1 PHD-type zinc finger and 1 RING-type zinc finger.
Synonyms: KIAA2023, SNF2, histone-linker, PHD and RING finger domain-containing helicase.
Antigène
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