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SREBF2 anticorps (AA 399-427)

Cet anticorps anti-SREBF2 Polyclonal Lapin (Clone RB24513) (ABIN654630) détecte spécifiquement SREBF2 dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.
N° du produit ABIN654630
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour SREBF2 anticorps (AA 399-427) (ABIN654630)

Antigène

Voir toutes SREBF2 Anticorps
SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Reactivité

  • 74
  • 34
  • 33
  • 16
  • 6
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 56
  • 19
Lapin

Clonalité

  • 57
  • 18
Polyclonal

Conjugué

  • 36
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SREBF2 est non-conjugé

Application

  • 52
  • 27
  • 20
  • 18
  • 11
  • 8
  • 7
  • 7
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB24513
Discover our top product SREBF2 Anticorps primaire

  • Épitope

    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 399-427

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This SREBF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the Central region of human SREBF2.

    Isotype

    Ig Fraction
  • anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 399-427) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 399-427) antibody

    SREBF2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 75-164) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 75-164) antibody

    SREBF2 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 833-1141) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 833-1141) antibody

    SREBF2 Reactivité: Humain WB, IP Hôte: Souris Monoclonal IgG-1C6 unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 801-900) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 801-900) antibody

    SREBF2 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) antibody

    SREBF2 Reactivité: Humain, Rat, Souris, Porc WB, IHC (p), IF (p) Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 455-469) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 455-469) antibody

    SREBF2 Reactivité: Humain WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 434-483) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 434-483) antibody

    SREBF2 Reactivité: Humain, Rat, Souris, Porc, Chien, Boeuf (Vache), Cobaye, Cheval, Poulet, Roussette (Chauve-souris), Hamster, Singe, Lapin WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 304-353) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 304-353) antibody

    SREBF2 Reactivité: Humain, Rat, Souris, Porc, Chien, Boeuf (Vache), Cobaye, Cheval, Poulet, Roussette (Chauve-souris), Hamster, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 402-431), (Middle Region) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 402-431), (Middle Region) antibody

    SREBF2 Reactivité: Humain WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated

    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 371-409) antibody
    anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 371-409) antibody

    SREBF2 Reactivité: Humain, Rat, Souris WB, ELISA, IF, ICC, FACS Hôte: Lapin Polyclonal unconjugated

  • Indications d'application

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

    Restrictions

    For Research Use only

  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months

  • Antigène

    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

    Autre désignation

    SREBF2

    Sujet

    SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors that play a critical role in lipid homeostasis by regulating genes involved in cholesterol and fatty acid metabolism. Each SREBP consists of three domains, including an amino-terminal transcription factor domain of ~480 amino acids, a middle hydrophobic region of ~80 amino acids containing two hydrophobic transmembrane segments, and a carboxy-terminal regulatory domain of ~590 amino acids. SREBP-2 regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway. SREBP-2 is ubiquitously detected in various tissues. Under basal conditions SREBP is bound to ER membranes as a glycosylated precursor protein. Upon cholesterol depletion, the protein is cleaved to its active forms (about 50-68 kDa) and translocated into the nucleus to stimulate transcription of genes involved in the uptake and synthesis of cholesterol.

    Poids moléculaire

    123688

    ID gène

    6721

    NCBI Accession

    NP_004590

    UniProt

    Q12772

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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