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SUV39H2 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement SUV39H2 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris. Il a été cité dans 3+ publications.
N° du produit ABIN388081
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour SUV39H2 anticorps (N-Term) (ABIN388081)

Antigène

Voir toutes SUV39H2 Anticorps
SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Reactivité

  • 75
  • 39
  • 34
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 73
  • 2
  • 1
Lapin

Clonalité

  • 56
  • 20
Polyclonal

Conjugué

  • 38
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Cet anticorp SUV39H2 est non-conjugé

Application

  • 59
  • 35
  • 34
  • 12
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB02737
  • Épitope

    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-122, N-Term

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This SUV39H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human SUV39H2.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Hung, Lin, Yeh, Chang: "Histone-modifying genes as biomarkers in hepatocellular carcinoma." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 5, pp. 2496-507, (2015) (PubMed).

    Chen, Yeh, Yang, Chang, Lee, Hung: "High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan." dans: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 513, (2013) (PubMed).

    Benlhabib, Mendelson: "Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia." dans: Molecular and cellular biology, Vol. 31, Issue 10, pp. 1949-58, (2011) (PubMed).

  • Antigène

    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

    Autre désignation

    SUV39H2

    Sujet

    The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59 % identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.

    Poids moléculaire

    46682

    ID gène

    79723

    NCBI Accession

    NP_001180353, NP_001180354, NP_001180355, NP_001180356, NP_078946

    UniProt

    Q9H5I1
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