Cet anticorps anti-TRPC6 Polyclonal Lapin (ABIN363063) détecte spécifiquement TRPC6 dans WB.
L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogène
peptide Corresponding to the amino terminal sequence derived from mouse TRPC6. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).