WASP anticorps
Aperçu rapide pour WASP anticorps (ABIN272092)
Antigène
Voir toutes WASP (WAS) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of WASP protein. (region surrounding Glu284)
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Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
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Purification
- Affinity Chromatography using epitope-specific immunogen.
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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 57-170) antibody
WAS Reactivité: Humain ELISA, IHC, FACS Hôte: Souris Monoclonal 7B10E4 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 39-251) antibodyWAS Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyVerified WAS Reactivité: Humain ELISA, IHC, FACS, IF Hôte: Chèvre Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 129-156), (C-Term) antibodyWAS Reactivité: Humain, Souris, Rat WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 116-144) antibodyWAS Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB23643 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 145-265) antibodyWAS Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyWAS Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 205-234) antibodyWAS Reactivité: Humain WB Hôte: Lapin Polyclonal RB40707 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 60-250) antibodyWAS Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 122-152), (Middle Region) antibodyWAS Reactivité: Humain, Souris WB, FACS, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sdium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
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Autre désignation
- WAS / IMD2
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Sujet
- The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome at Xp11.23. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a 53 kDa proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.Synonyms: WASp, Wiskott-Aldrich syndrome protein
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Poids moléculaire
- approx. 53 kDa
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ID gène
- 7454
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NCBI Accession
- NP_000368
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UniProt
- P42768
Antigène
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