WNT1 anticorps (Internal Region)
(1 reference)
Aperçu rapide pour WNT1 anticorps (Internal Region) (ABIN233837)
Antigène
Voir toutes WNT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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N° du produit (Fournisseur)
- 600-401-a37
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Fournisseur
- Rockland
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Fonction
- Wnt1 Antibody
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Réactivité croisée (Details)
- This antibody reacts with human and mouse Wnt1 protein.
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Attributs du produit
- Synonyms: rabbit anti-WNT-1 antibody, rabbit anti-WNT1 antibody, INT1 antibody, Murine mammary tumor virus integration site 1 antibody, Oncogene INT1 antibody, Proto oncogene protein Wnt 1 antibody, Wingless type MMTV integration site family member 1 antibody
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Purification
- This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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Stérilité
- Sterile filtered
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Immunogène
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human Wnt1 protein.
Immunogen Type: Conjugated Peptide
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Isotype
- IgG
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anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (AA 231-370) antibody
WNT1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (AA 251-350) antibodyWNT1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (C-Term) antibodyWNT1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) antibodyWNT1 Reactivité: Humain, Souris WB, IHC, ELISA, FACS, ICC Hôte: Souris Monoclonal 10C8 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (AA 260-288) antibodyWNT1 Reactivité: Humain, Souris WB, IHC, ELISA, FACS Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (AA 260-288), (C-Term) antibodyWNT1 Reactivité: Humain, Souris WB, IHC (p), FACS Hôte: Lapin Polyclonal RB19186 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (Internal Region) antibodyWNT1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Cheval, Lapin IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (Middle Region) antibodyWNT1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (C-Term) antibodyWNT1 Reactivité: Humain, Souris WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (C-Term) antibodyWNT1 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blotting.
Western Blot Dilution: 1:1,500 - 1:6,000
ELISA Dilution: 1:25,000
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.38 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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: "Wnt pathway activation in long term remnant rat model." dans: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).
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- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
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Autre désignation
- WNT1
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Sujet
- Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98 % identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.
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ID gène
- 7471, 4885655
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UniProt
- P04628
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Pathways
- Signalisation WNT, Dopaminergic Neurogenesis
Antigène
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