anti-24-Dehydrocholesterol Reductase (DHCR24) Anticorps

DHCR24 encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. De plus, nous expédions Seladin 1 Protéines (7) et Seladin 1 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DHCR24 1718 Q15392
DHCR24 74754 Q8VCH6
DHCR24 298298  
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Top anti-Seladin 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 55 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-DHCR24 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate Host: Rabbit <br /> Target Name: DHCR24 <br /> Sample Tissue: Human Fetal Heart <br /> Antibody Dilution: 1.0 µg/mL 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-DHCR24 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of anti-DHCR24 Antibody (Center)(ABIN389353) in HepG2 cell line lysates (35 µg/lane). DHCR24 (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of anti-DHCR24 Antibody (N-term) (ABIN389352) in HepG2 cell line lysates (35 µg/lane). DHCR24 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-DHCR24 Antibody (N-term) (ABIN389352) in mouse liver tissue lysates (35 µg/lane). DHCR24 (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using Seladin 1, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Seladin 1, antibody at 1:200 dilution. 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in Microplate Reader by 450nm 100 μL Connectez-vous pour afficher 3 to 7 Days
$295.90
Détails

DHCR24 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Seladin 1 Anticorps mieux référencés

  1. Human Polyclonal Seladin 1 Primary Antibody pour WB - ABIN514969 : Gilk, Cockrell, Luterbach, Hansen, Knodler, Ibarra, Steele-Mortimer, Heinzen: Bacterial colonization of host cells in the absence of cholesterol. dans PLoS pathogens 2013 (PubMed)

Plus d’anticorps contre Seladin 1 partenaires d’interaction

Human 24-Dehydrocholesterol Reductase (DHCR24) interaction partners

  1. DHCR24 auto-antibody represents a potential noninvasive biomarker for hepatitis C virus-related liver disease and may facilitate the diagnosis of PIVKA-II and AFP (Montrer AFP Anticorps)-negative hepatocellular carcinoma.

  2. physical and functional interaction between DHCR24 and DHCR7 (Montrer DHCR7 Anticorps)

  3. In vitro experiments showed that DHCR24 overexpression induced tumor proliferation.

  4. Data (including data from studies using RNA from post-mortem brain tissue) suggest that expression of DHCR24 is up-regulated in parietal cortex of patients with Huntington's disease as compared to control subjects.

  5. Data indicate a mechanism whereby 3beta-hydroxysterol Delta24-reductase (DHCR24) activity is regulated by signaling.

  6. DHCR24 expression protects neuronal cells from apoptotic cell death induced by endoplasmic reticulum stress.

  7. TR-beta (Montrer TXNRD2 Anticorps) and LXR-alpha (Montrer NR1H3 Anticorps) competitively up-regulate the human Seladin-1 promoter, sharing the same response element, site A.

  8. DHCR24 gene expression is regulation by cholesterol availability.

  9. a novel role for 24,25EC in cholesterol homeostasis, through its rapid inhibition of cholesterol synthesis at DHCR24.

  10. a gender dependent effect of DHCR24 rs600491 polymorphism on the susceptibility to Alzheimer disease.

Mouse (Murine) 24-Dehydrocholesterol Reductase (DHCR24) interaction partners

  1. When DHCR24 is genetically deleted there is a decreased association of EAAT2 (Montrer SLC1A2 Anticorps) with lipid rafts after ischemia.

  2. Data (including data from transgenic mice) suggest that expression of Dhcr24 is down-regulated in brain tissues of mice exhibiting symptoms modeling advanced Huntington's disease.

  3. RE1-silencing transcription factor (Montrer REST Anticorps) acts because it is bound in close proximity to SREBP, thus amplifying its ability to upregulate 24-dehydrocholesterol reductase

  4. concluded that TH up-regulates Seladin-1 gene expression at the transcriptional level and LXR-alpha (Montrer NR1H3 Anticorps) maintains the gene expression

  5. This is the first demonstration that DHCR24 plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.

  6. Seladin-1 is shown to be an LPS (Montrer TLR4 Anticorps)-responsive gene that negatively regulates the TNF- alpha (Montrer TNF Anticorps) production and bone resorption in response to LPS (Montrer TLR4 Anticorps).

  7. Seladin-1-dependent cholesterol synthesis is involved in lowering Abeta (Montrer APP Anticorps) levels.

  8. cellular cholesterol biosynthesis is critical for the activation and maintenance of the Akt (Montrer AKT1 Anticorps)-Bad cell survival cascade in response to growth factors such as insulin (Montrer INS Anticorps).

  9. Cholesterol homeostasis in Dhcr24 knockout mice is characterized by strong activation of liver X receptor-targeted genes and by mechanisms compensating for cholesterol depletion.

  10. ablation of DHCR24/seladin-1 prevented apoptosis of primary neurons in a p53 (Montrer TP53 Anticorps)-dependent manner

Seladin 1 (DHCR24) profil antigène

Profil protéine

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Gene names and symbols associated with DHCR24

  • 24-dehydrocholesterol reductase (DHCR24) anticorps
  • 24-dehydrocholesterol reductase (dhcr24) anticorps
  • 24-dehydrocholesterol reductase (AaeL_AAEL012138) anticorps
  • 24-dehydrocholesterol reductase (CpipJ_CPIJ000670) anticorps
  • 24-dehydrocholesterol reductase (Dhcr24) anticorps
  • 2310076D10Rik anticorps
  • 5830417J06Rik anticorps
  • DCE anticorps
  • MGC82737 anticorps
  • mKIAA0018 anticorps
  • Nbla03646 anticorps
  • seladin-1 anticorps
  • SELADIN1 anticorps
  • zgc:101638 anticorps

Protein level used designations for DHCR24

24-dehydrocholesterol reductase , 3 beta-hydroxysterol delta 24-reductase , 3-beta-hydroxysterol delta-24-reductase , delta(24)-sterol reductase , desmosterol-to-cholesterol enzyme , diminuto/dwarf1 homolog , seladin 1 , selective AD indicator 1 , 3-beta-hydroxysterol delta-24 reductase , seladin-1

GENE ID SPECIES
424661 Gallus gallus
447786 Xenopus laevis
456879 Pan troglodytes
489573 Canis lupus familiaris
494102 Danio rerio
549554 Xenopus (Silurana) tropicalis
5575872 Aedes aegypti
6031429 Culex quinquefasciatus
100546716 Meleagris gallopavo
100584832 Nomascus leucogenys
1718 Homo sapiens
74754 Mus musculus
298298 Rattus norvegicus
533726 Bos taurus
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