anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) Anticorps

ATIC encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. De plus, nous expédions ATIC Protéines (12) et ATIC Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ATIC 471 P31939
ATIC 108147 Q9CWJ9
ATIC 81643 O35567
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Top anti-ATIC Anticorps sur anticorps-enligne.fr

Showing 10 out of 74 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-ATIC Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate <b>Sample Type:</b> 1. Hamster CHO K1 cells (20ug)<br>2. HeLa skin cells(20ug)<br>3. HEK273 cells (20ug)<br>4. Human Skin Fibroblats (100ug)<br><b>Primary Dilution:</b> 1:800<br><b>Secondary Antibody:</b> Clean-Blot IP detection Reagent and Kit<br><b>Secondary Dilution:</b> 1:2000<br><b>Image Submitted By:</b> V. Skopova, M. Zikanova<br>Institute of Inherited Metabolic Disorders, Charles University in Prague and General Hopspital in Prague 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Fruit Fly Souris Inconjugué IHC (p), WB 0.1 mg Connectez-vous pour afficher 3 to 4 Days
$271.76
Détails
Boeuf (Vache) Souris Inconjugué IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with ATIC antibody ABIN214223 at 15 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Fruit Fly Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Souris Inconjugué WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC. 100 μL Connectez-vous pour afficher 2 to 3 Days
$423.50
Détails
Humain Souris Inconjugué WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC. 100 μL Connectez-vous pour afficher 2 to 3 Days
$423.50
Détails
Humain Souris Inconjugué FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC. 100 μL Connectez-vous pour afficher 2 to 3 Days
$482.90
Détails
Chien Souris Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Chien Souris Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails

ATIC Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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anti-ATIC Anticorps mieux référencés

  1. Fruit Fly (Drosophila melanogaster) Monoclonal ATIC Primary Antibody pour IHC (p), WB - ABIN2477543 : Rattan, Giri, Singh, Singh: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. dans The Journal of biological chemistry 2005 (PubMed)

Plus d’anticorps contre ATIC partenaires d’interaction

Human 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) interaction partners

  1. Pediatric Osteosarcoma patients with ATIC 347C>G exhibited a good histologic response to chemotherapy

  2. The ATIC 347 C/G polymorphism may be associated with non-responsiveness to and or toxicity of methotrexate in Caucasian rheumatoid arthritis patients.

  3. ATIC 347C>G gene polymorphism may be associated with the development of MTX (Montrer MTX1 Anticorps) induced gastrointestinal adverse events.

  4. genotyping of ATIC rs2372536 and ITPA (Montrer ITPA Anticorps) rs1127354 variants or measuring ITPA (Montrer ITPA Anticorps) activity could be useful to predict methotrexate response in children with juvenile idiopathic arthritis.

  5. This study shows that polymorphisms on genes related to the metabolic pathway of pemetrexed, especially, ATIC and GGH (Montrer GGH Anticorps) genes, would have a therapeutic implication in pemetrexed-treated patients with lung adenocarcinoma

  6. Our data show that ATIC is in complex with insulin receptor (IR (Montrer INSR Anticorps))and siRNA-mediated partial knockdown of ATIC in HEK293 cells, decreases IR tyrosine phosphorylation and regulates IR endocytosis. Insulin (Montrer INS Anticorps) stimulation and ATIC knockdown readily increase level of AMPK (Montrer PRKAA1 Anticorps)-Thr172 phosphorylation in IR complexes.ATIC depletion delayed insulin (Montrer INS Anticorps) response of Glut2 (Montrer SLC2A2 Anticorps) translocation in HEK293 cells and decreased AKT (Montrer AKT1 Anticorps)-Ser473 phosphorylation.

  7. Single nucleotide polymorphisms in ATIC gene is associated with acute graft-versus-host disease.

  8. MTHFR (Montrer MTHFR Anticorps), DHFR (Montrer DHFR Anticorps) and ATIC genetic variants can be considered as pharmacogenetic markers of outcome in RA patients under MTX (Montrer MTX1 Anticorps) monotherapy.

  9. study suggests that MTHFR (Montrer MTHFR Anticorps) C677T and ATIC T675C genotyping combined with clinicopathological data may help to identify patients whom will not benefit from MTX (Montrer MTX1 Anticorps) treatment and, therefore, assist clinicians in personalizing RA treatment

  10. Results proved in cultured skin fibroblasts from patients with AICA-ribosiduria that various mutations of ATIC destabilize to various degrees purinosome assembly.

ATIC profil antigène

Profil protéine

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Gene names and symbols associated with ATIC

  • 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (atic) anticorps
  • bifunctional purine biosynthesis protein PurH (purH) anticorps
  • bifunctional purine biosynthesis protein purH (purH) anticorps
  • Bifunctional purine biosynthesis protein purH (purH) anticorps
  • Bifunctional purine biosynthesis protein PurH (purH) anticorps
  • 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) anticorps
  • 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Atic) anticorps
  • 2610509C24Rik anticorps
  • AA536954 anticorps
  • AICAR anticorps
  • AICARFT anticorps
  • AW212393 anticorps
  • IMPCHASE anticorps
  • purH anticorps

Protein level used designations for ATIC

bifunctional purine biosynthesis protein PurH , bifunctional purine biosynthesis protein purH , Bifunctional purine biosynthesis protein purH , Bifunctional purine biosynthesis protein PurH , 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase , AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme , AICARFT/IMPCHASE , bifunctional purine biosynthesis protein PURH , phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase , 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase, ATIC , aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase , aminoimidazole-4-carboxamide ribonucleotidetransformylase/IMP cyclohydrolase , bifunctional purine biosynthesis protein

GENE ID SPECIES
735175 Xenopus laevis
1064322 Tropheryma whipplei TW08/27
1795643 Rhodopirellula baltica SH 1
3726377 Carboxydothermus hydrogenoformans Z-2901
3852615 Salinibacter ruber DSM 13855
4056143 Baumannia cicadellinicola str. Hc (Homalodisca coagulata)
4289939 Hyphomonas neptunium ATCC 15444
6413645 Cellvibrio japonicus Ueda107
6944185 Coprothermobacter proteolyticus DSM 5265
6945486 Dictyoglomus thermophilum H-6-12
7355505 Thermomicrobium roseum DSM 5159
8213748 Teredinibacter turnerae T7901
8220261 Neorickettsia risticii str. Illinois
8867387 Deferribacter desulfuricans SSM1
8984725 Bacillus megaterium QM B1551
8996427 Salinibacter ruber M8
9115672 Bacillus megaterium DSM 319
9399564 Leuconostoc gasicomitatum LMG 18811
9444476 Clostridium ljungdahlii DSM 13528
9486490 Candidatus Nitrospira defluvii
9728858 Streptococcus pneumoniae 670-6B
9773527 Paenibacillus polymyxa E681
9796745 Arthrobacter arilaitensis Re117
9902632 Rothia dentocariosa ATCC 17931
9904419 Gardnerella vaginalis ATCC 14019
10101946 Candidatus Blochmannia vafer str. BVAF
10974211 Zobellia galactanivorans
471 Homo sapiens
396091 Gallus gallus
488513 Canis lupus familiaris
100170854 Sus scrofa
506343 Bos taurus
108147 Mus musculus
81643 Rattus norvegicus
100346623 Oryctolagus cuniculus
Fournisseurs de qualité sélectionnés pour anti-ATIC (ATIC) Anticorps
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