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ADAMTS13 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. De plus, nous expédions ADAMTS13 Kits (28) et ADAMTS13 Protéines (6) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 86 products:
Human Polyclonal ADAMTS13 Primary Antibody pour EIA, IHC (p) - ABIN359601
Levy, Nichols, Lian, Foroud, McClintick, McGee, Yang, Siemieniak, Stark, Gruppo, Sarode, Shurin, Chandrasekaran, Stabler, Sabio, Bouhassira, Upshaw, Ginsburg, Tsai: Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. dans Nature 2001
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Human Polyclonal ADAMTS13 Primary Antibody pour WB - ABIN152016
Tao, Wang, Choi, Bernardo, Nishio, Sadler, López, Dong: Cleavage of ultralarge multimers of von Willebrand factor by C-terminal-truncated mutants of ADAMTS-13 under flow. dans Blood 2005
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Human Polyclonal ADAMTS13 Primary Antibody pour ELISA, IHC - ABIN4278265
Ganburged, Suda, Saito, Yamazaki, Isokawa, Moriyama: Dilated capillaries, disorganized collagen fibers and differential gene expression in periodontal ligaments of hypomorphic fibrillin-1 mice. dans Cell and tissue research 2010
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Human Polyclonal ADAMTS13 Primary Antibody pour IHC (p), WB - ABIN391641
Zheng, Chung, Takayama, Majerus, Sadler, Fujikawa: Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. dans The Journal of biological chemistry 2001
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Human Polyclonal ADAMTS13 Primary Antibody pour IP, WB - ABIN251718
Feng, Eyler, Zhang, Maga, Nester, Kroll, Smith, Afshar-Kharghan: Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome. dans Blood 2013
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Human Polyclonal ADAMTS13 Primary Antibody pour WB - ABIN251717
Turner, Nolasco, Ruggeri, Moake: Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage. dans Blood 2009
Results also suggest that Toxoplasma gondii-mediated apoptosis might play a pivotal role and a different type of role in the mechanism of neurodegeneration and neuropathology in the process of toxoplasma encephalitis. Furthermore, expression of ADAMTS-13 might give an idea of the progress and is critical for diagnosis of this disease.
Letter: deficiency of ADAMTS13 results in increased formation of venous thrombosis in mice.
ADAMTS13 substrate specificity
Data indicate that the p.D187H mutation impairs ADAMTS13 activity and secretion and may contribute to thrombotic thrombocytopenic purpura.
Data show that metalloendopeptidase (Montrer THOP1 Anticorps) ADAMTS13 does not directly promote development of adipose tissue.
findings provide further evidence on the pathophysiological role for the ADAMTS13/VWF (Montrer VWF Anticorps) axis in atherosclerosis
Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor (Montrer VWF Anticorps) string formation under flow in a free-thiol-dependent manner.
The results indicate that the microvascular process induced by ADAMTS13 deficiency triggers complement activation on platelets and the endothelium, which may contribute to formation of thrombotic microangiopathy.
model of acute myocardial infarction in ADAMTS13 gene deleted (Adamts13 -/-) mice
We hypothesize that ADAMTS13 protects brain from ischemia-reperfusion injury by regulating von Willebrand factor (Montrer VWF Anticorps) -dependent inflammation as well as microvascular plugging
Two novel ADAMTS13 mutations (p.I143T and p.Y570C) identified in two adolescence onset congenital thrombotic thrombocytopenic purpura patients were studied. Proteasome degradation of these ADAMTS13 mutants contributed to their reduced secretion.
Correlation between ADAMTS13 activity and neurological impairment in acute thrombotic microangiopathy patients.
review to introduce the state of progress with respect to some of the theorized roles of ADAMTS13[review]
IL-8 (Montrer IL8 Anticorps), TNF-alpha (Montrer TNF Anticorps), tissue factor (Montrer F3 Anticorps), IL-8 (Montrer IL8 Anticorps)+tissue factor (Montrer F3 Anticorps) and TNF-alpha (Montrer TNF Anticorps)+tissue factor (Montrer F3 Anticorps) decreased the levels of ADAMTS13 secreted by umbilical vein endothelial cells.
Significantly lower ADAMTS-13 levels and significantly higher VWF (Montrer VWF Anticorps) antigen levels were concluded to be the result of a pathological process rather than an etiological factor for Venous thromboembolism.
ADAMTS13 and VWF (Montrer VWF Anticorps) are co-expressed in microvascular endothelial cells.
ADAMTS13-a disintegrin-like metalloproteinase with thrombospondin motif type 1 member 13-regulates a key physiological process of coagulation in the circulation by cleaving VWF (Montrer VWF Anticorps) multimers into small, inactive fragments. Low levels of ADAMTS13 in the blood may play a role in cardiovascular and hematological disorders, and clarifying its role may help improve disease management.
ADAMTS13 activity, d-Dimer and cystatin C (Montrer CST3 Anticorps) are associated with retinopathy in type 1 diabetic patients and are promising biomarkers for the diagnosis and monitoring of diabetic retinopathy
von Willebrand factor (Montrer VWF Anticorps) and ADAMTS-13 are associated with the occurrence of venous thromboembolism in patients with cancer.
ADAMTS13 does not appear to be associated to disease severity or the hemodynamic derangement in patients with cirrhosis.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
ADAM metallopeptidase with thrombospondin type 1 motif, 13
, ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like
, A disintegrin and metalloproteinase with thrombospondin motifs 13-like
, ADAM metallopeptidase with thrombospondin type 1 motif, 12
, A disintegrin and metalloproteinase with thrombospondin motifs 12
, A disintegrin and metalloproteinase with thrombospondin motifs 13
, ADAM-TS 13
, ADAMTS13 isoform IAP-b
, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
, vWF-CP mRNA for von Willebrand factor-cleaving
, vWF-cleaving protease
, von Willebrand factor-cleaving protease
, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13