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anti-ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) Anticorps

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. De plus, nous expédions ATG4B Protéines (13) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ATG4B 23192 Q9Y4P1
ATG4B 66615 Q8BGE6
ATG4B 316640  
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Top anti-ATG4B Anticorps sur anticorps-enligne.fr

Showing 10 out of 180 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-APG4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Raji cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-ATG4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Placenta 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ATG4B AntibodyTitration: 2.5 µg/mL  Positive Control: RajiATG4B is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of APG4B (arrow) using purified polyclonal antibody (ABIN388497). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the APG4B gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human skeletal muscle reacted with Autophagy APG4B Antibody (E273)(ABIN388497), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué WB ATG4B/MB10290 antibody   western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ATG4B/MB10290  antibody detected the ATG4B/MB10290 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-hAPG4B-R31 Pab (ABIN388494) in 293 cell line lysates transiently transfected with the ATG4B gene (2 µg/lane). hAPG4B-R31(arrow) was detected using the purified polyclonal antibody (1:60 dilution). The anti-APG4B Pab (ABIN388494) is used in Western blot to detect APG4B in CEM tissue lysate 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. APG4B / ATG4B Antibody used in Western blot to detect APG4B in CEM tissue lysate. 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human skeletal muscle reacted with Autophagy AAPG4B / ATG4B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of APG4B (arrow) using APG4B / ATG4B Antibody . 293 cell lysates (2 ug/lane) either non transfected (Lane 1) or transiently transfected with the APG4B gene (Lane 2) (Origene Technologies). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué IF, IHC (p), WB Western blot analysis of anti-hAPG4B-373 Pab (ABIN1882065) in 293 cell line lysates transiently transfected with the ATG4B gene (2 µg/lane). hAPG4B-373(arrow) was detected using the purified Pab. Western blot analysis of anti-hAPG4B-373 Pab (ABIN1882065) in 293 cell line lysates transiently transfected with the ATG4B gene (2 µg/lane). hAPG4B-373(arrow) was detected using the purified Pab. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ATG4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human kidney WB Suggested Anti-ATG4B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human kidney 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails

ATG4B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ATG4B Anticorps mieux référencés

  1. Human Polyclonal ATG4B Primary Antibody pour IHC (p), WB - ABIN388494 : Baehrecke: Autophagy: dual roles in life and death? dans Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 6 references for ABIN388494

  2. Human Polyclonal ATG4B Primary Antibody pour IF, IHC (p) - ABIN1882065 : Pontén, Westermark: Properties of human malignant glioma cells in vitro. dans Medical biology 1978 (PubMed)
    Show all 6 references for ABIN1882065

  3. Human Polyclonal ATG4B Primary Antibody pour EIA, IHC (p) - ABIN1449637 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. dans Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 6 references for ABIN1449637

  4. Human Polyclonal ATG4B Primary Antibody pour EIA, IHC (p) - ABIN1449638 : Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. dans Developmental cell 2005 (PubMed)
    Show all 5 references for ABIN1449638

  5. Human Polyclonal ATG4B Primary Antibody pour IHC (p), WB - ABIN388497 : Tanida, Sou, Ezaki, Minematsu-Ikeguchi, Ueno, Kominami: HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN388497

  6. Human Monoclonal ATG4B Primary Antibody pour WB - ABIN659121 : Satoo, Noda, Kumeta, Fujioka, Mizushima, Ohsumi, Inagaki: The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. dans The EMBO journal 2009 (PubMed)

  7. Cow (Bovine) Polyclonal ATG4B Primary Antibody pour IHC, WB - ABIN2787433 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. dans Cell 2006 (PubMed)

  8. Cow (Bovine) Polyclonal ATG4B Primary Antibody pour WB - ABIN2775794 : Kumanomidou, Mizushima, Komatsu, Suzuki, Tanida, Sou, Ueno, Kominami, Tanaka, Yamane: The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers. dans Journal of molecular biology 2005 (PubMed)

Plus d’anticorps contre ATG4B partenaires d’interaction

Arabidopsis thaliana ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. These results support the conclusion that CML24 affects autophagy progression through interactions with ATG4.

  2. AtATG4a is catalytically more active and has broad AtATG8 substrate specificity compared with AtATG4b. [ATG4b]

Xenopus laevis ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

Human ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. The results have interesting implications that SLC27A4 (Montrer SLC27A4 Anticorps)/ATG4B complex might be conducive to the occurrence of autophagy in human cancer cells, which is meaningful investigations toward the aim of developing autophagy-targeting drugs and have significant values in clinical application.

  2. Results demonstrated that upregulation of miR (Montrer MLXIP Anticorps)-34a by transfection or demethylation resulted in the enhanced apoptosis and drug sensitivity in prostate cancer cells. ATG4B, directly regulated by miR (Montrer MLXIP Anticorps)-34a through AMPK (Montrer PRKAA1 Anticorps)/mTOR (Montrer FRAP1 Anticorps), was involved in this process.

  3. Purified ATG4B protein interact with LC3B (Montrer MAP1LC3B Anticorps) in vitro.

  4. ATG4B independently plays a role as a positive regulator on tumor proliferation and a negative regulator on autophagy in colorectal cancer cells.

  5. This study identifies ATG4B as a potential biomarker for predicting therapeutic response in treatment-naive chronic myeloid leukemia (Montrer BCL11A Anticorps) stem/progenitor cells and uncovers ATG4B as a possible drug target in these cells.

  6. The actions of ATG4 family members (particularly ATG4B) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts.

  7. Atg4B possessed the broadest spectrum against all substrates, followed by Atg4A (Montrer ATG4A Anticorps) for ATG8 (Montrer GABARAPL2 Anticorps) substrates

  8. HsAtg4B negatively regulates the localization of LC3 (Montrer MAP1LC3A Anticorps) to a membrane compartment by delipidation

  9. crystal structure of human Atg4b by X-ray crystallography at 2.0 A resolution, and show that Atg4b is a cysteine protease (Montrer CTSB Anticorps) whose active catalytic triad site consists of Cys74, His280 and Asp278

  10. Murine Atg8L/Apg8L (Montrer GABARAPL1 Anticorps) modification is mediated by human Atg4B.

Mouse (Murine) ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. miR (Montrer MLXIP Anticorps)-34a might regulate the autophagic activity and can cause injury in ischemia reperfusion injured renal tubular epithelial cells (RTEC) via targeting Atg4B. Atg4B knockdown inhibited autophagy in RTECs.

  2. the ATG4B protease and autophagy play a crucial role protecting epithelial cells against bleomycin-induced stress and apoptosis

  3. REDD1 (Montrer DDIT4 Anticorps)/TXNIP (Montrer TXNIP Anticorps) complex expression is sufficient to induce reactive oxygen species, suppress ATG4B activity and activate autophagy.

  4. these findings demonstrate a role for Ser (Montrer SIGLEC1 Anticorps)-383 and Ser (Montrer SIGLEC1 Anticorps)-392 phosphorylation of ATG4B in control of autophagy.

  5. mTOR (Montrer FRAP1 Anticorps) inhibition alleviates Huntington's disease progression by inducing Atg4b-dependent autophagic flux.

  6. An autophagy-related gene, Atg4b, is identified as a de novo target gene of C/EBP BETA (Montrer CEBPB Anticorps) and is shown to play an important role in 3T3-L1 adipocyte differentiation.

  7. the RNF5-mediated control of membranalATG4B reveals a novel layer in the regulation of LC3 (Montrer MAP1LC3A Anticorps) processing and autophagy.

  8. The Atg4b participates in polarized secretion of lysosomal contents into the extracellular space by directing lysosomes to fuse with the plasma membrane.

  9. Genetic inactivation of mouse Atg4b resulted in amorphous globular bodies in the neuropil of the deep cerebellar nuclei and adjacent vestibular nuclei and a mild but measurable impairment of motor performance on the Rotarod.

  10. The Apg4B/autophagin-1 protease thus serves as a processing/deconjugating enzyme for these four highly divergent mammalian Apg8 homologues, GATE-16 (Montrer GABARAPL2 Anticorps), MAP1 (Montrer MOAP1 Anticorps)-LC3 (Montrer MAP1LC3A Anticorps), GABARAP (Montrer GABARAP Anticorps), and Apg8L (Montrer GABARAPL1 Anticorps).

ATG4B profil antigène

Profil protéine

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with ATG4B

  • autophagy related 4B, cysteine peptidase (ATG4B) anticorps
  • autophagy-related 4b (Atg4b) anticorps
  • cysteine protease ATG4b (AT3G59950) anticorps
  • cysteine protease ATG4B (Tsp_08582) anticorps
  • cysteine protease ATG4B (Tsp_11599) anticorps
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) (atg4b) anticorps
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) (ATG4B) anticorps
  • autophagy related 4B, cysteine peptidase (atg4b) anticorps
  • autophagy related 4B, cysteine peptidase (Atg4b) anticorps
  • 2510009N07Rik anticorps
  • Apg4b anticorps
  • Atg4bl anticorps
  • Aut2b2 anticorps
  • Autl1 anticorps
  • AW048066 anticorps

Protein level used designations for ATG4B

ATG4 autophagy related 4 homolog B , cysteine protease ATG4B , autophagy 4b variant 1Cysteine protease ATG4B , autophagy 4b variant 3 , cysteine protease ATG4b , APG4 autophagy 4 homolog B , autophagy-related protein 4 homolog B , AUT2B , autophagin-2B , autophagy-related cysteine endopeptidase 2B , cAut2B , AUT-like 1 cysteine endopeptidase , autophagin-1 , autophagy-related cysteine endopeptidase 1 , hAPG4B , APG4 (ATG4) autophagy-related homolog B , AUT-like 1, cysteine endopeptidase , autophagin 1 , autophagy-related 4B , cysteine protease involved in autophagy APG4-B , autophagy related 4 homolog B , autophagy related 4-like protein B , bAut2B

GENE ID SPECIES
748674 Pan troglodytes
100067797 Equus caballus
100240691 Zea mays
825165 Arabidopsis thaliana
10907016 Trichinella spiralis
10912977 Trichinella spiralis
100194746 Salmo salar
448859 Danio rerio
404750 Gallus gallus
494717 Xenopus laevis
23192 Homo sapiens
66615 Mus musculus
316640 Rattus norvegicus
609599 Canis lupus familiaris
100462747 Sus scrofa
408002 Bos taurus
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