ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Kits ELISA

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps (280) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits ELISA sur anticorps-enligne.fr

Showing 4 out of 21 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Rat 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Humain 0.076 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 2 to 3 Days
$779.90
Détails
Souris 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 2 to 3 Days
$779.90
Détails
Rat
0.312 ng/mL - 20 ng/mL   96 Tests Connectez-vous pour afficher 8 to 12 Days
$790.25
Détails

Plus Kits ELISA pour ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d'interaction

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Kits ELISA), Bcrp (Montrer ABCG2 Kits ELISA) and Mrp1 (Montrer ABCC1 Kits ELISA) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (Montrer ABCB4 Kits ELISA)--{REVIEW}

  2. Studied ABCB1 protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1-expressing neurons in the left habenula.

  3. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (Montrer ABCC6 Kits ELISA), ABCB1 and CYP2C8 (Montrer CYP2C8 Kits ELISA) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

  4. The authors found that transient TUBB3 (Montrer TUBB3 Kits ELISA) activation, through ABCB1, in response to the stimulation of FOXO3a (Montrer FOXO3 Kits ELISA) expression, significantly contributes to the cross-resistance of the paclitaxel-resistant cell population and consequently limits the efficacy of both agents where cancer cells have developed multiple resistance.

  5. MDR1 and CYP3A5 (Montrer CYP3A5 Kits ELISA) genetic polymorphisms significantly influence plasma trough levels and therapeutic response of imatinib in patients with chronic myeloid leukemia (Montrer BCL11A Kits ELISA). Patients with GG genotype for CYP3A5 (Montrer CYP3A5 Kits ELISA)-A6986G (P=0.016) and TT genotype for MDR1-C3435T (P=0.013) polymorphisms had significantly higher trough levels of imatinib.

  6. Rescue experiments confirmed the combined role of LUCAT1, miR (Montrer MLXIP Kits ELISA)-200c and ABCB1 on osteosarcoma proliferation, invasion and methotrexate resistance. Overall, results indicate the vital role of LUCAT1 in the methotrexate resistance regulation through miR (Montrer MLXIP Kits ELISA)-200c/ABCB1 pathway, providing a novel insight and treatment strategy for osteosarcoma drug resistance.

  7. Mdr1 enforces T Cell homeostasis in the presence of intestinal bile acids.

  8. Data show that co-treated with vincristine and XL019, a inhibitor of JAK2 and P-glycoprotein (P-gp), up-regulated expression of p21 and phosphorylated H2A histone family, member X (pH2AX).

  9. Tangeretin could sensitize ABCB1-overexpressing cancer cells to chemotherapeutical agents by directly inhibiting ABCB1 transporter function.

  10. over-functional P-gp (Montrer ABCB4 Kits ELISA) might play an important role in the pathogenesis of ITP (Montrer ITPA Kits ELISA) and induce GCs (Montrer GCLC Kits ELISA) resistance in nonresponsive ITP (Montrer ITPA Kits ELISA) patients. The blockage of P-gp (Montrer ABCB4 Kits ELISA) could be a promising therapeutic approach for GCs (Montrer GCLC Kits ELISA)-resistant patients with ITP (Montrer ITPA Kits ELISA).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. conclusion, MDR1 (Montrer ABCB4 Kits ELISA) and BCRP (Montrer ABCG2 Kits ELISA) are expressed on apical membranes of the rodent placental SynT (Montrer STX1A Kits ELISA)-II layer.

  2. Mdr1 (Montrer ABCB4 Kits ELISA) enforces T Cell homeostasis in the presence of intestinal bile acids.

  3. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  4. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Kits ELISA) ATPase (Montrer DNAH8 Kits ELISA) activity

  5. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  6. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Kits ELISA) activity and reverse the up-regulated P-gp (Montrer ABCB4 Kits ELISA) and MDR1 (Montrer ABCB4 Kits ELISA) levels induced by artemisinin.

  7. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Kits ELISA) gene expression and activity in an enantiomer-specific way.

  8. Pgp (Montrer ABCB4 Kits ELISA)-coupled ATPase (Montrer DNAH8 Kits ELISA) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  9. Data show that human transgenic mutant huntingtin (Montrer HTT Kits ELISA) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Kits ELISA)) which suggests that MDR1 (Montrer ABCB4 Kits ELISA) might be a potential therapeutic target for Huntington's disease.

  10. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Kits ELISA) B1 by the HMG-CoA reductase (Montrer HMGCR Kits ELISA) inhibitor simvastatin

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) anticorps
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) anticorps
  • ATP binding cassette subfamily B member 1A (Abcb1a) anticorps
  • ATP binding cassette subfamily B member 1 (Abcb1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • malic enzyme complex, mitochondrial (Mod2) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • Cd243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • Mdr anticorps
  • Mdr-1 anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • Mod-2 anticorps
  • Mod-2r anticorps
  • Mod-2s anticorps
  • Mod2-r anticorps
  • Mod2-s anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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